Hearing the effects on output through the amp

I'm using a new interfact (m-audio fast track ultra) and have had no issues with set up. I've got my guitar going through input 1 and out to my amp - no problem. But - I don't hear any the pedal effects on output. I hear them on the track recording - but, is it not possible to hear the effects on output? My amp is connected to the m-audio output so, my assumption - which may be incorrect - is that garageband is feeding the m-audio via the USB 2 connection, thus, any applied effects would be audible on output.
Perhaps I'm all wrong - though I'm hopeful that I just have a configuration issue.
Many thanks if anyone has any info that will help.

and take them in and out at different parts of the song.
GarageBand does not offer effect automation.
This may help:
http://www.thegaragedoor.com/tutorials/automation.html 
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