HT201276 How to unfreeze Mac in Force Quit Applications? Only mouse isresponding.

Mac desktop was frozen in Firefox. I used the option-command-esc and this did not unlock. Also, shut down with on-off switch, unpluged, and held on-off for over 1 minute. Rebooted and now getting a file with question mark flashing. Any ideas out there?

It's clear that something is happening, and I think it's the hard drive.
As your Mac is frozen, hold the Power button to turn it off. Then, insert the OS X DVD and hold the C key while your Mac is starting to start up from the DVD. Choose your language, go to Utilities menu (on the menu bar) > Disk Utility, select Macintosh HD in the sidebar and verify the drive. If it gives you an error, repair it. What does Disk Utility say after repairing the drive?

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