Issue when trying to launch Handbrake, problem report generated

I've posted this over in the Handrake forums but soi far I haven't had a response.  I'm hoping someone here might be able to point me in a direction.  I've suddenly been unable to launch Handbrake.  Every time I try the icon bounce once or twice on the dock then a Problem Report dialog opens up with this information;
I've tried deleting the files in ~Library/Application Support/Handbrake and the related Handbrake files in ~Library/Preferences. I've tried the latest nightly build, I've tried repairing permissions, and nothing works.
Process: HandBrake [4624]
Path: /Applications/Handbrake/HandBrake.app/Contents/MacOS/HandBrake
Identifier: fr.handbrake.HandBrake
Version: 4810svn x86_64 (2012070401)
Code Type: X86-64 (Native)
Parent Process: launchd [498]
Date/Time: 2012-07-04 21:32:10.654 -0400
OS Version: Mac OS X Server 10.7.4 (11E53)
Report Version: 9
Interval Since Last Report: 326864 sec
Crashes Since Last Report: 27
Per-App Interval Since Last Report: 155 sec
Per-App Crashes Since Last Report: 4
Anonymous UUID: 5CD59213-7D18-42C1-9DBD-522B15266524
Crashed Thread: 0 Dispatch queue: com.apple.main-thread
Exception Type: EXC_BAD_ACCESS (SIGBUS)
Exception Codes: 0x000000000000000a, 0x0000000101aa9228
VM Regions Near 0x101aa9228:
CoreImage 0000000101aa8000-0000000101aa9000 [ 4K] rw-/rwx SM=PRV
--> mapped file 0000000101aa9000-0000000101aaa000 [ 4K] rw-/rwx SM=PRV /Users/*/Library/Caches/*/*.maps
shared memory 0000000101aaa000-0000000101aac000 [ 8K] rw-/rw- SM=SHM
Application Specific Information:
objc[4624]: garbage collection is OFF
Thread 0 Crashed:: Dispatch queue: com.apple.main-thread
0 libCoreFSCache.dylib 0x0000000101aa2455 fscache_open + 809
1 libcldcpuengine.dylib 0x0000000102fb4aa9 init_fscache + 633
2 libsystem_c.dylib 0x00007fff84c3be06 pthread_once + 86
3 libcldcpuengine.dylib 0x0000000102fb4189 cld_createkernels + 441
4 libcldcpuengine.dylib 0x0000000102fb2c3f glrCompBuildProgram + 97
5 com.apple.opencl 0x00007fff8b59e3b4 clBuildProgram + 3182
6 com.apple.CoreImage 0x00007fff8878d531 -[FEOpenCLContext _loadKernel:target:testOnly:] + 1330
7 com.apple.CoreImage 0x00007fff8888beb8 -[FEContext(Kernel) loadKernel:target:] + 96
8 com.apple.CoreImage 0x00007fff887c88cc FEApplyTreeNode::render1(FETreeContext*, FEShape const&, fe_kernel_target_struct*, int, float*, FETreeTexture*) + 100
9 com.apple.CoreImage 0x00007fff887c9899 FEApplyTreeNode::render2(FETreeContext*, FEShape const*, void (*)(FEContext*, void*, FEFormat), void (*)(FEContext*, void*), void*) + 1589
10 com.apple.CoreImage 0x00007fff887c6df9 FETreeNode::render_(FETreeContext*, FEShape const*, void (*)(FEContext*, void*, FEFormat), void (*)(FEContext*, void*), void*) + 149
11 com.apple.CoreImage 0x00007fff887ca684 FETreeNode::render(FETreeContext*, FEShape const&, void (*)(FEContext*, void*, FEFormat), void (*)(FEContext*, void*), void*) + 108
12 com.apple.CoreImage 0x00007fff887ce422 FETreeContext::renderTree(FETreeNode*, FEShape const&, void (*)(FEContext*, void*, FEFormat), void (*)(FEContext*, void*), void*) + 276
13 com.apple.CoreImage 0x00007fff887ce736 FETreeContext::renderImage_(FEImage*, CGRect, FEShape const*, CGAffineTransform, CGColorSpace*, FEFormat, bool, void (*)(FEContext*, void*, FEFormat), void (*)(FEContext*, void*), void*) + 688
14 com.apple.CoreImage 0x00007fff887ce9bf FETreeContext::renderImage(FEImage*, CGRect, FEShape const*, CGAffineTransform, CGColorSpace*, FEFormat, bool, void (*)(FEContext*, void*, FEFormat), void (*)(FEContext*, void*), void*) + 375
15 com.apple.CoreImage 0x00007fff887a5617 -[FEImage(Internal) _renderWithContext:bounds:transform:colorSpace:format:premultiplied:setupCallba ck:finishCallback:callbackData:] + 247
16 com.apple.CoreImage 0x00007fff887a4c39 -[FEImage getBitmap:withContext:origin:transform:colorSpace:] + 678
17 com.apple.CoreImage 0x00007fff8875aeb9 -[CIContextImpl render:toBitmap:rowBytes:bounds:format:colorSpace:] + 349
18 com.apple.CoreImage 0x00007fff88759ef6 -[CIContext render:toBitmap:rowBytes:bounds:format:colorSpace:] + 91
19 libCGXCoreImage.A.dylib 0x00007fff838562e5 cgxcoreimage_instance_render + 2301
20 libCGXCoreImage.A.dylib 0x00007fff83855927 cgxcoreimage_provider_create_data + 52
21 libCGXCoreImage.A.dylib 0x00007fff8385587d faultDataAcquireBytePointer + 154
22 com.apple.CoreGraphics 0x00007fff88c4b3c8 CGAccessSessionGetBytePointer + 45
23 com.apple.CoreGraphics 0x00007fff88c74463 img_decode_read + 234
24 com.apple.CoreGraphics 0x00007fff88c7429b img_colormatch_read + 363
25 com.apple.CoreGraphics 0x00007fff88c740e5 img_alphamerge_read + 532
26 com.apple.CoreGraphics 0x00007fff88c71ccb img_data_lock + 8307
27 com.apple.CoreGraphics 0x00007fff88cf5209 CGSImageDataLock + 186
28 libRIP.A.dylib 0x00007fff86953d4a ripc_AcquireImage + 2209
29 libRIP.A.dylib 0x00007fff8695258c ripc_DrawImage + 1048
30 com.apple.CoreGraphics 0x00007fff88cf4d72 CGContextDrawImage + 434
31 com.apple.coreui 0x00007fff8b166570 CUIPenCG::DrawImage(void*, CGRect, void*) + 70
32 com.apple.coreui 0x00007fff8b16e0ef CUIRenderer::DrawImage(CGRect, long, CUIDescriptor const*) + 4821
33 com.apple.coreui 0x00007fff8b13e002 CUIRenderer::Draw(CGRect, CGContext*, __CFDictionary const*, __CFDictionary const**) + 4646
34 com.apple.coreui 0x00007fff8b1639a4 CUIDraw + 225
35 com.apple.AppKit 0x00007fff81bfe4b0 -[NSCoreUIImageRep draw] + 179
36 com.apple.AppKit 0x00007fff81bfe37e -[NSImageRep drawInRect:] + 341
37 com.apple.AppKit 0x00007fff81bfe21c __-[NSImageRep drawInRect:fromRect:operation:fraction:respectFlipped:hints:]_block_invoke_2 + 111
38 com.apple.AppKit 0x00007fff81bfe0a0 NSGraphicsContextPushContextWithFlippedMetadata_drawWithBlock_ + 318
39 com.apple.AppKit 0x00007fff81b91803 __-[NSImageRep drawInRect:fromRect:operation:fraction:respectFlipped:hints:]_block_invoke_1 + 1953
40 com.apple.AppKit 0x00007fff81b90eaf -[NSImageRep drawInRect:fromRect:operation:fraction:respectFlipped:hints:] + 1212
41 com.apple.AppKit 0x00007fff81bc1066 -[NSImage _drawMappingAlignmentRectToRect:withState:backgroundStyle:operation:fraction:fl ip:hints:] + 2443
42 com.apple.AppKit 0x00007fff81db25ed -[NSPopUpButtonCell _drawIndicatorWithFrame:inView:] + 401
43 com.apple.AppKit 0x00007fff81c1bb7e -[NSPopUpButtonCell drawBorderAndBackgroundWithFrame:inView:] + 269
44 com.apple.AppKit 0x00007fff81c1ba00 -[NSMenuItemCell drawWithFrame:inView:] + 270
45 com.apple.AppKit 0x00007fff81bbcdb7 -[NSControl drawRect:] + 398
46 com.apple.AppKit 0x00007fff81b8897a -[NSView _drawRect:clip:] + 3758
47 com.apple.AppKit 0x00007fff81bb5b4f -[NSView _recursiveDisplayAllDirtyWithLockFocus:visRect:] + 1583
48 com.apple.AppKit 0x00007fff81bb5f7b -[NSView _recursiveDisplayAllDirtyWithLockFocus:visRect:] + 2651
49 com.apple.AppKit 0x00007fff81bb5f7b -[NSView _recursiveDisplayAllDirtyWithLockFocus:visRect:] + 2651
50 com.apple.AppKit 0x00007fff81b85f55 -[NSView _recursiveDisplayRectIfNeededIgnoringOpacity:isVisibleRect:rectIsVisibleRectFor View:topView:] + 1032
51 com.apple.AppKit 0x00007fff81b8086f -[NSView _displayRectIgnoringOpacity:isVisibleRect:rectIsVisibleRectForView:] + 4755
52 com.apple.AppKit 0x00007fff81b792ed -[NSView displayIfNeeded] + 1676
53 com.apple.AppKit 0x00007fff81f184ee -[NSDrawer(NSDrawerPrivate) _displayIfNeeded] + 94
54 com.apple.AppKit 0x00007fff81c37999 -[NSWindow(NSDrawerSupportPrivate) _displayAllDrawersIfNeeded] + 123
55 com.apple.AppKit 0x00007fff81c367ac -[NSWindow _reallyDoOrderWindow:relativeTo:findKey:forCounter:force:isModal:] + 795
56 com.apple.AppKit 0x00007fff81c363a8 -[NSWindow _doOrderWindow:relativeTo:findKey:forCounter:force:isModal:] + 807
57 com.apple.AppKit 0x00007fff81c3602c -[NSWindow orderWindow:relativeTo:] + 154
58 com.apple.AppKit 0x00007fff81c358cd -[NSWindow makeKeyAndOrderFront:] + 49
59 fr.handbrake.HandBrake 0x0000000100017bd4 -[HBController applicationDidFinishLaunching:] + 1613
60 com.apple.Foundation 0x00007fff83363d0e __-[NSNotificationCenter addObserver:selector:name:object:]_block_invoke_1 + 47
61 com.apple.CoreFoundation 0x00007fff867347ba _CFXNotificationPost + 2634
62 com.apple.Foundation 0x00007fff8334ffc3 -[NSNotificationCenter postNotificationName:object:userInfo:] + 65
63 com.apple.AppKit 0x00007fff81b414e3 -[NSApplication _postDidFinishNotification] + 212
64 com.apple.AppKit 0x00007fff81b41249 -[NSApplication _sendFinishLaunchingNotification] + 78
65 com.apple.AppKit 0x00007fff81b3ff10 -[NSApplication(NSAppleEventHandling) _handleAEOpenEvent:] + 242
66 com.apple.AppKit 0x00007fff81b3fc71 -[NSApplication(NSAppleEventHandling) _handleCoreEvent:withReplyEvent:] + 330
67 com.apple.CoreFoundation 0x00007fff8677e541 -[NSObject performSelector:withObject:withObject:] + 65
68 com.apple.Foundation 0x00007fff833867c7 __-[NSAppleEventManager setEventHandler:andSelector:forEventClass:andEventID:]_block_invoke_1 + 101
69 com.apple.Foundation 0x00007fff8338574e -[NSAppleEventManager dispatchRawAppleEvent:withRawReply:handlerRefCon:] + 283
70 com.apple.Foundation 0x00007fff833855dc _NSAppleEventManagerGenericHandler + 105
71 com.apple.AE 0x00007fff836e7c25 aeDispatchAppleEvent(AEDesc const*, AEDesc*, unsigned int, unsigned char*) + 200
72 com.apple.AE 0x00007fff836e7b03 _ZL25dispatchEventAndSendReplyPK6AEDescPS_ + 38
73 com.apple.AE 0x00007fff836e79f7 aeProcessAppleEvent + 250
74 com.apple.HIToolbox 0x00007fff8e69ed7d AEProcessAppleEvent + 102
75 com.apple.AppKit 0x00007fff81b3d07d _DPSNextEvent + 1247
76 com.apple.AppKit 0x00007fff81b3c735 -[NSApplication nextEventMatchingMask:untilDate:inMode:dequeue:] + 135
77 com.apple.AppKit 0x00007fff81b39071 -[NSApplication run] + 470
78 com.apple.AppKit 0x00007fff81db5244 NSApplicationMain + 867
79 fr.handbrake.HandBrake 0x00000001000017b4 start + 52
Thread 1:: Dispatch queue: com.apple.libdispatch-manager
0 libsystem_kernel.dylib 0x00007fff8691d7e6 kevent + 10
1 libdispatch.dylib 0x00007fff8767078a _dispatch_mgr_invoke + 923
2 libdispatch.dylib 0x00007fff8766f31a _dispatch_mgr_thread + 54
Thread 2:: Dispatch queue: CFPreferences Background Sync Queue
0 libsystem_kernel.dylib 0x00007fff8691de9e stat$INODE64 + 10
1 com.apple.CoreFoundation 0x00007fff8670535a _CFGetPathProperties + 90
2 com.apple.CoreFoundation 0x00007fff867052ba _CFGetFileProperties + 122
3 com.apple.CoreFoundation 0x00007fff868060c3 -[CFXPreferencesPropertyListSourceSynchronizer _canFLockAtURL:] + 115
4 com.apple.CoreFoundation 0x00007fff867311d2 -[CFXPreferencesPropertyListSourceSynchronizer synchronize] + 98
5 com.apple.CoreFoundation 0x00007fff8676f81f __-[CFXPreferencesPropertyListSource synchronizeInBackgroundWithCompletionBlock:]_block_invoke_1 + 111
6 libdispatch.dylib 0x00007fff8766ea86 _dispatch_call_block_and_release + 18
7 libdispatch.dylib 0x00007fff876702d6 _dispatch_queue_drain + 264
8 libdispatch.dylib 0x00007fff87670132 _dispatch_queue_invoke + 54
9 libdispatch.dylib 0x00007fff8766f92c _dispatch_worker_thread2 + 198
10 libsystem_c.dylib 0x00007fff84c3e3da _pthread_wqthread + 316
11 libsystem_c.dylib 0x00007fff84c3fb85 start_wqthread + 13
Thread 3:
0 libsystem_kernel.dylib 0x00007fff8691ce42 __semwait_signal + 10
1 libsystem_c.dylib 0x00007fff84bf2dea nanosleep + 164
2 libsystem_c.dylib 0x00007fff84bf2bb5 usleep + 53
3 fr.handbrake.HandBrake 0x000000010006e012 thread_func + 466
4 fr.handbrake.HandBrake 0x0000000100074c67 hb_thread_func + 55
5 libsystem_c.dylib 0x00007fff84c3c8bf _pthread_start + 335
6 libsystem_c.dylib 0x00007fff84c3fb75 thread_start + 13
Thread 4:
0 libsystem_kernel.dylib 0x00007fff8691ce42 __semwait_signal + 10
1 libsystem_c.dylib 0x00007fff84bf2dea nanosleep + 164
2 libsystem_c.dylib 0x00007fff84bf2bb5 usleep + 53
3 fr.handbrake.HandBrake 0x000000010006e012 thread_func + 466
4 fr.handbrake.HandBrake 0x0000000100074c67 hb_thread_func + 55
5 libsystem_c.dylib 0x00007fff84c3c8bf _pthread_start + 335
6 libsystem_c.dylib 0x00007fff84c3fb75 thread_start + 13
Thread 5:
0 libsystem_kernel.dylib 0x00007fff8691ce42 __semwait_signal + 10
1 libsystem_c.dylib 0x00007fff84bf2dea nanosleep + 164
2 libsystem_c.dylib 0x00007fff84bf2bb5 usleep + 53
3 fr.handbrake.HandBrake 0x000000010006e012 thread_func + 466
4 fr.handbrake.HandBrake 0x0000000100074c67 hb_thread_func + 55
5 libsystem_c.dylib 0x00007fff84c3c8bf _pthread_start + 335
6 libsystem_c.dylib 0x00007fff84c3fb75 thread_start + 13
Thread 6:
Thread 0 crashed with X86 Thread State (64-bit):
rax: 0x00000001064bebb0 rbx: 0x00000001064bc480 rcx: 0x00000001064bebb8 rdx: 0x0000000000000bec
rdi: 0x00000001019dd000 rsi: 0x0000000000000008 rbp: 0x00007fff5fbf7220 rsp: 0x00007fff5fbf6f70
r8: 0x0000000000000003 r9: 0x0000000000000bea r10: 0x0000000000000000 r11: 0x00000000fffffff7
r12: 0x0000000101aa9000 r13: 0x00000001064bc3f0 r14: 0x0000000000000000 r15: 0x0000000000000000
rip: 0x0000000101aa2455 rfl: 0x0000000000010206 cr2: 0x0000000101aa9228
Logical CPU: 0
Binary Images:
0x100000000 - 0x10105dfd7 +fr.handbrake.HandBrake (4810svn x86_64 - 2012070401) <EDCD3447-34D4-3B9A-9BE9-83B03E776270> /Applications/Handbrake/HandBrake.app/Contents/MacOS/HandBrake
0x10185d000 - 0x101869ff7 +com.growl.growlframework (1.2.2 - 1.2.2) <C76D2B1C-5455-CFCA-6470-B8B171C14A16> /Applications/Handbrake/HandBrake.app/Contents/Frameworks/Growl.framework/Versi ons/A/Growl
0x101875000 - 0x10188bfff +org.andymatuschak.Sparkle (1.5 Beta 6 - 313) <B4628320-468B-F473-EBD3-4303D9C5B639> /Applications/Handbrake/HandBrake.app/Contents/Frameworks/Sparkle.framework/Ver sions/A/Sparkle
0x1018a4000 - 0x101987fff libcrypto.0.9.7.dylib (0.9.7 - compatibility 0.9.7) <358B5B40-43B2-3F92-9FD3-DAA68806E1FF> /usr/lib/libcrypto.0.9.7.dylib
0x101aa1000 - 0x101aa4ff7 libCoreFSCache.dylib (??? - ???) <70D5EB80-24F5-3837-9302-EBD4CFCE5CBA> /System/Library/Frameworks/OpenGL.framework/Versions/A/Libraries/libCoreFSCache .dylib
0x102fb0000 - 0x102fb6fef libcldcpuengine.dylib (1.50.69 - compatibility 1.0.0) <303313AD-2D57-37A5-922B-3194C5DCD007> /System/Library/Frameworks/OpenCL.framework/Libraries/libcldcpuengine.dylib
0x1047a5000 - 0x104caeff7 com.apple.RawCamera.bundle (3.14.0 - 646) <75A96BFC-1832-808B-F430-C4C9379C5A98> /System/Library/CoreServices/RawCamera.bundle/Contents/MacOS/RawCamera
0x7fff6e23d000 - 0x7fff6e271baf dyld (195.6 - ???) <C58DAD8A-4B00-3676-8637-93D6FDE73147> /usr/lib/dyld
0x7fff81a8f000 - 0x7fff81a8ffff com.apple.Cocoa (6.6 - ???) <7EC4D759-B2A6-3A99-AC75-809FED1500C6> /System/Library/Frameworks/Cocoa.framework/Versions/A/Cocoa
0x7fff81ae4000 - 0x7fff81ae9fff libpam.2.dylib (3.0.0 - compatibility 3.0.0) <D952F17B-200A-3A23-B9B2-7C1F7AC19189> /usr/lib/libpam.2.dylib
0x7fff81aea000 - 0x7fff81b1dff7 com.apple.GSS (2.2 - 2.0) <971395D0-B9D0-3FDE-B23F-6F9D0A2FB95F> /System/Library/Frameworks/GSS.framework/Versions/A/GSS
0x7fff81b34000 - 0x7fff8273aff7 com.apple.AppKit (6.7.3 - 1138.47) <CAF5783F-F80B-30E7-929F-BBA6D96C5C44> /System/Library/Frameworks/AppKit.framework/Versions/C/AppKit
0x7fff8273b000 - 0x7fff82842fe7 libsqlite3.dylib (9.6.0 - compatibility 9.0.0) <EE02BB01-64C9-304D-9719-A35F5CD6D04C> /usr/lib/libsqlite3.dylib
0x7fff82847000 - 0x7fff8284cfff libGIF.dylib (??? - ???) <8763F67F-A881-30B6-B20E-D395B4D9FD58> /System/Library/Frameworks/ApplicationServices.framework/Versions/A/Frameworks/ ImageIO.framework/Versions/A/Resources/libGIF.dylib
0x7fff8284d000 - 0x7fff829d7ff7 com.apple.WebKit (7534.56 - 7534.56.5) <BC22A17F-A32F-3D9B-926F-091A47C4B315> /System/Library/Frameworks/WebKit.framework/Versions/A/WebKit
0x7fff829d8000 - 0x7fff82b77ff7 com.apple.QuartzCore (1.7 - 270.4) <97E20A5F-652B-3E85-8C46-DCB777248ECD> /System/Library/Frameworks/QuartzCore.framework/Versions/A/QuartzCore
0x7fff82b78000 - 0x7fff82c3fff7 com.apple.ColorSync (4.7.4 - 4.7.4) <590AFCDA-F10E-31FE-9B01-DA5FFE74C2BB> /System/Library/Frameworks/ApplicationServices.framework/Versions/A/Frameworks/ ColorSync.framework/Versions/A/ColorSync
0x7fff82c40000 - 0x7fff82cdaff7 com.apple.SearchKit (1.4.0 - 1.4.0) <4E70C394-773E-3A4B-A93C-59A88ABA9509> /System/Library/Frameworks/CoreServices.framework/Versions/A/Frameworks/SearchK it.framework/Versions/A/SearchKit
0x7fff82fc3000 - 0x7fff82ff0fe7 libSystem.B.dylib (159.1.0 - compatibility 1.0.0) <DA79E5BA-BBA3-3768-AAD8-B34BA877EF03> /usr/lib/libSystem.B.dylib
0x7fff82ff1000 - 0x7fff83010fff libresolv.9.dylib (46.1.0 - compatibility 1.0.0) <0635C52D-DD53-3721-A488-4C6E95607A74> /usr/lib/libresolv.9.dylib
0x7fff83011000 - 0x7fff83073ff7 com.apple.Symbolication (1.3 - 91) <0945ACAF-AA0A-3D01-9960-72B51722EC1F> /System/Library/PrivateFrameworks/Symbolication.framework/Versions/A/Symbolicat ion
0x7fff83074000 - 0x7fff830bbff7 com.apple.CoreMedia (1.0 - 705.78) <F6EA2328-FD3E-3057-80C7-C9845837F863> /System/Library/Frameworks/CoreMedia.framework/Versions/A/CoreMedia
0x7fff830bc000 - 0x7fff8310ffff com.apple.AppleVAFramework (5.0.14 - 5.0.14) <E3FE9B47-2276-3316-B2D2-85784AD2D9B3> /System/Library/PrivateFrameworks/AppleVA.framework/Versions/A/AppleVA
0x7fff83110000 - 0x7fff83138fff com.apple.PerformanceAnalysis (1.11 - 11) <8D4C6382-DD92-37A2-BCFC-E89951320848> /System/Library/PrivateFrameworks/PerformanceAnalysis.framework/Versions/A/Perf ormanceAnalysis
0x7fff83139000 - 0x7fff8321de5f libobjc.A.dylib (228.0.0 - compatibility 1.0.0) <871E688B-CF57-3BC7-80D6-F6476DFF109B> /usr/lib/libobjc.A.dylib
0x7fff83248000 - 0x7fff83249ff7 libsystem_blocks.dylib (53.0.0 - compatibility 1.0.0) <8BCA214A-8992-34B2-A8B9-B74DEACA1869> /usr/lib/system/libsystem_blocks.dylib
0x7fff8324a000 - 0x7fff8334cfff libxml2.2.dylib (10.3.0 - compatibility 10.0.0) <AFBB22B7-07AE-3F2E-B88C-70BEEBFB8A86> /usr/lib/libxml2.2.dylib
0x7fff8334d000 - 0x7fff83666fff com.apple.Foundation (6.7.2 - 833.25) <22AAC369-B63C-3C55-8AC6-C3ECBA44DA7B> /System/Library/Frameworks/Foundation.framework/Versions/C/Foundation
0x7fff836e4000 - 0x7fff83723fff com.apple.AE (527.7 - 527.7) <B82F7ABC-AC8B-3507-B029-969DD5CA813D> /System/Library/Frameworks/CoreServices.framework/Versions/A/Frameworks/AE.fram ework/Versions/A/AE
0x7fff83724000 - 0x7fff83728fff libdyld.dylib (195.5.0 - compatibility 1.0.0) <380C3F44-0CA7-3514-8080-46D1C9DF4FCD> /usr/lib/system/libdyld.dylib
0x7fff83729000 - 0x7fff8372fff7 libunwind.dylib (30.0.0 - compatibility 1.0.0) <1E9C6C8C-CBE8-3F4B-A5B5-E03E3AB53231> /usr/lib/system/libunwind.dylib
0x7fff83730000 - 0x7fff83740ff7 com.apple.opengl (1.7.7 - 1.7.7) <0CA11278-746C-353A-923B-BCC0047190C3> /System/Library/Frameworks/OpenGL.framework/Versions/A/OpenGL
0x7fff83741000 - 0x7fff83746fff libcache.dylib (47.0.0 - compatibility 1.0.0) <1571C3AB-BCB2-38CD-B3B2-C5FC3F927C6A> /usr/lib/system/libcache.dylib
0x7fff83811000 - 0x7fff83852fff com.apple.QD (3.40 - ???) <47674D2C-BE88-388E-B1B0-03F08BFFE5FD> /System/Library/Frameworks/ApplicationServices.framework/Versions/A/Frameworks/ QD.framework/Versions/A/QD
0x7fff83853000 - 0x7fff8385afff libCGXCoreImage.A.dylib (600.0.0 - compatibility 64.0.0) <B3F07872-63B1-3AAF-A313-9B2886822C58> /System/Library/Frameworks/ApplicationServices.framework/Versions/A/Frameworks/ CoreGraphics.framework/Versions/A/Resources/libCGXCoreImage.A.dylib
0x7fff8396b000 - 0x7fff839c3fff libTIFF.dylib (??? - ???) <A0FF68DE-2935-30E7-B61C-4D9D70E14AD0> /System/Library/Frameworks/ApplicationServices.framework/Versions/A/Frameworks/ ImageIO.framework/Versions/A/Resources/libTIFF.dylib
0x7fff839c4000 - 0x7fff83a77ff7 com.apple.CoreText (220.20.0 - ???) <0E979362-15E4-3955-BF54-B5961361D1CC> /System/Library/Frameworks/ApplicationServices.framework/Versions/A/Frameworks/ CoreText.framework/Versions/A/CoreText
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0x7fff8b309000 - 0x7fff8b320fff com.apple.CFOpenDirectory (10.7 - 146) <E71AE4A2-F72B-35F2-9043-9F45CF75F11A> /System/Library/Frameworks/OpenDirectory.framework/Versions/A/Frameworks/CFOpen Directory.framework/Versions/A/CFOpenDirectory
0x7fff8b3a9000 - 0x7fff8b3ebff7 libcommonCrypto.dylib (55010.0.0 - compatibility 1.0.0) <BB770C22-8C57-365A-8716-4A3C36AE7BFB> /usr/lib/system/libcommonCrypto.dylib
0x7fff8b3ec000 - 0x7fff8b3f3ff7 com.apple.CommerceCore (1.0 - 17) <3894FE48-EDCE-30E9-9796-E2F959D92704> /System/Library/PrivateFrameworks/CommerceKit.framework/Versions/A/Frameworks/C ommerceCore.framework/Versions/A/CommerceCore
0x7fff8b3f4000 - 0x7fff8b3f9fff libcompiler_rt.dylib (6.0.0 - compatibility 1.0.0) <98ECD5F6-E85C-32A5-98CD-8911230CB66A> /usr/lib/system/libcompiler_rt.dylib
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0x7fff8b3ff000 - 0x7fff8b423fff com.apple.Kerberos (1.0 - 1) <1F826BCE-DA8F-381D-9C4C-A36AA0EA1CB9> /System/Library/Frameworks/Kerberos.framework/Versions/A/Kerberos
0x7fff8b424000 - 0x7fff8b48fff7 com.apple.framework.IOKit (2.0 - ???) <6C604894-7F61-3130-8499-20791D14577F> /System/Library/Frameworks/IOKit.framework/Versions/A/IOKit
0x7fff8b57b000 - 0x7fff8b57efff com.apple.help (1.3.2 - 42) <BF14DE49-F7E8-336F-81FB-BBDF2DB3AC09> /System/Library/Frameworks/Carbon.framework/Versions/A/Frameworks/Help.framewor k/Versions/A/Help
0x7fff8b57f000 - 0x7fff8b596fff com.apple.MultitouchSupport.framework (231.4 - 231.4) <10A978D1-8781-33F0-BE45-60C9171F7278> /System/Library/PrivateFrameworks/MultitouchSupport.framework/Versions/A/Multit ouchSupport
0x7fff8b597000 - 0x7fff8b5c4ff7 com.apple.opencl (1.50.69 - 1.50.69) <57939F7D-3626-30E2-883D-8A7CCB3F8763> /System/Library/Frameworks/OpenCL.framework/Versions/A/OpenCL
0x7fff8bac9000 - 0x7fff8bb4dff7 com.apple.ApplicationServices.ATS (317.11.0 - ???) <082DEAFE-8A93-3AF2-B4E5-30012E725929> /System/Library/Frameworks/ApplicationServices.framework/Versions/A/Frameworks/ ATS.framework/Versions/A/ATS
0x7fff8bb4e000 - 0x7fff8bb4efff com.apple.audio.units.AudioUnit (1.7.2 - 1.7.2) <04C10813-CCE5-3333-8C72-E8E35E417B3B> /System/Library/Frameworks/AudioUnit.framework/Versions/A/AudioUnit
0x7fff8bb4f000 - 0x7fff8bb51fff libCVMSPluginSupport.dylib (??? - ???) <1C73D331-6F6C-3872-A011-1C41FBF49F2A> /System/Library/Frameworks/OpenGL.framework/Versions/A/Libraries/libCVMSPluginS upport.dylib
0x7fff8bb52000 - 0x7fff8bb54ff7 com.apple.print.framework.Print (7.4 - 247.3) <626C58D5-2841-3329-8C32-9F4A8353F3E7> /System/Library/Frameworks/Carbon.framework/Versions/A/Frameworks/Print.framewo rk/Versions/A/Print
0x7fff8bb64000 - 0x7fff8bd8efe7 com.apple.CoreData (104.1 - 358.14) <6BB64605-8DA7-337D-A2AB-A3346A421CBD> /System/Library/Frameworks/CoreData.framework/Versions/A/CoreData
0x7fff8bd8f000 - 0x7fff8be30ff7 com.apple.LaunchServices (480.33 - 480.33) <45EF2044-3396-3910-9B5B-C8F7777D5F56> /System/Library/Frameworks/CoreServices.framework/Versions/A/Frameworks/LaunchS ervices.framework/Versions/A/LaunchServices
0x7fff8be3a000 - 0x7fff8be3dfff libCoreVMClient.dylib (??? - ???) <934D0D11-C34F-3C06-A352-21BB8FFE9774> /System/Library/Frameworks/OpenGL.framework/Versions/A/Libraries/libCoreVMClien t.dylib
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0x7fff8cb59000 - 0x7fff8cb59fff com.apple.vecLib (3.7 - vecLib 3.7) <9A58105C-B36E-35B5-812C-4ED693F2618F> /System/Library/Frameworks/vecLib.framework/Versions/A/vecLib
0x7fff8cb5a000 - 0x7fff8cbcdfff libstdc++.6.dylib (52.0.0 - compatibility 7.0.0) <6BDD43E4-A4B1-379E-9ED5-8C713653DFF2> /usr/lib/libstdc++.6.dylib
0x7fff8cbce000 - 0x7fff8cbf7fff com.apple.CoreVideo (1.7 - 70.3) <9A9D4058-9935-3B0A-B1A6-27EB78D02249> /System/Library/Frameworks/CoreVideo.framework/Versions/A/CoreVideo
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0x7fff8cdcc000 - 0x7fff8ce71fff com.apple.ink.framework (1.4 - 110) <F93B76B3-E57C-3805-B20D-03717A3F91DD> /System/Library/Frameworks/Carbon.framework/Versions/A/Frameworks/Ink.framework /Versions/A/Ink
0x7fff8ce72000 - 0x7fff8cef7ff7 com.apple.Heimdal (2.2 - 2.0) <FF0BD9A4-6FB0-31E3-ABFB-563FBBEC45FC> /System/Library/PrivateFrameworks/Heimdal.framework/Versions/A/Heimdal
0x7fff8cef8000 - 0x7fff8cef9fff libunc.dylib (24.0.0 - compatibility 1.0.0) <337960EE-0A85-3DD0-A760-7134CF4C0AFF> /usr/lib/system/libunc.dylib
0x7fff8cf23000 - 0x7fff8d002ff7 com.apple.ImageIO.framework (3.1.2 - 3.1.2) <FFA7532B-336A-3F0B-9AB9-2A35B56ED887> /System/Library/Frameworks/ApplicationServices.framework/Versions/A/Frameworks/ ImageIO.framework/Versions/A/ImageIO
0x7fff8d078000 - 0x7fff8d079fff libdnsinfo.dylib (395.11.0 - compatibility 1.0.0) <853BAAA5-270F-3FDC-B025-D448DB72E1C3> /usr/lib/system/libdnsinfo.dylib
0x7fff8d0c4000 - 0x7fff8d0c9fff com.apple.OpenDirectory (10.7 - 146) <7960A302-F9AC-3F72-838E-3A382032DCA6> /System/Library/Frameworks/OpenDirectory.framework/Versions/A/OpenDirectory
0x7fff8d0ca000 - 0x7fff8de01fff com.apple.WebCore (7534.56 - 7534.56.5) <4E63291C-539E-32E3-8B1C-EA8E546B3159> /System/Library/Frameworks/WebKit.framework/Versions/A/Frameworks/WebCore.frame work/Versions/A/WebCore
0x7fff8de02000 - 0x7fff8de42ff7 libcups.2.dylib (2.9.0 - compatibility 2.0.0) <5328C0AB-F169-3786-A3EC-9E82E960CAAF> /usr/lib/libcups.2.dylib
0x7fff8de43000 - 0x7fff8e165fe7 com.apple.JavaScriptCore (7534.56 - 7534.56.6) <675725F8-37C4-3B80-ADB0-7B6AE908A908> /System/Library/Frameworks/JavaScriptCore.framework/Versions/A/JavaScriptCore
0x7fff8e166000 - 0x7fff8e166fff com.apple.ApplicationServices (41 - 41) <89B6AD5B-5C75-3E83-8C2B-AA7F4C55E400> /System/Library/Frameworks/ApplicationServices.framework/Versions/A/Application Services
0x7fff8e178000 - 0x7fff8e5abff7 com.apple.VideoToolbox (1.0 - 705.78) <7F115540-88CF-3087-951A-7073F7D58F4D> /System/Library/PrivateFrameworks/VideoToolbox.framework/Versions/A/VideoToolbo x
0x7fff8e5ac000 - 0x7fff8e5e7fff libsystem_info.dylib (??? - ???) <35F90252-2AE1-32C5-8D34-782C614D9639> /usr/lib/system/libsystem_info.dylib
0x7fff8e5e8000 - 0x7fff8e5fefff libGL.dylib (??? - ???) <6A473BF9-4D35-34C6-9F8B-86B68091A9AF> /System/Library/Frameworks/OpenGL.framework/Versions/A/Libraries/libGL.dylib
0x7fff8e68e000 - 0x7fff8e9baff7 com.apple.HIToolbox (1.9 - ???) <B7D2A06B-7BE5-3355-BF7D-8139100B9B97> /System/Library/Frameworks/Carbon.framework/Versions/A/Frameworks/HIToolbox.fra mework/Versions/A/HIToolbox
0x7fff8e9bb000 - 0x7fff8e9e6ff7 com.apple.CoreServicesInternal (113.17 - 113.17) <B1DF81C3-9C23-3BAE-9DE8-21EAFEEB97B8> /System/Library/PrivateFrameworks/CoreServicesInternal.framework/Versions/A/Cor eServicesInternal
0x7fff8e9e7000 - 0x7fff8eaf3fff libcrypto.0.9.8.dylib (44.0.0 - compatibility 0.9. <3A8E1F89-5E26-3C8B-B538-81F5D61DBF8A> /usr/lib/libcrypto.0.9.8.dylib
External Modification Summary:
Calls made by other processes targeting this process:
task_for_pid: 6
thread_create: 0
thread_set_state: 0
Calls made by this process:
task_for_pid: 0
thread_create: 0
thread_set_state: 0
Calls made by all processes on this machine:
task_for_pid: 3816
thread_create: 0
thread_set_state: 0
VM Region Summary:
ReadOnly portion of Libraries: Total=204.5M resident=121.1M(59%) swapped_out_or_unallocated=83.4M(41%)
Writable regions: Total=55.0M written=5588K(10%) resident=9124K(16%) swapped_out=0K(0%) unallocated=46.1M(84%)
REGION TYPE VIRTUAL
=========== =======
CG backing stores 836K
CG image 72K
CG raster data 64K
CG shared images 3408K
CoreAnimation 12K
CoreGraphics 16K
CoreImage 4K
CoreServices 6924K
MALLOC 34.1M
MALLOC guard page 48K
Memory tag=240 4K
Memory tag=242 12K
STACK GUARD 56.0M
Stack 10.5M
Stack (reserved) 520K reserved VM address space (unallocated)
VM_ALLOCATE 316K
__CI_BITMAP 80K
__DATA 23.0M
__IMAGE 528K
__LINKEDIT 49.7M
__RC_CAMERAS 248K
__TEXT 154.8M
__UNICODE 544K
mapped file 38.8M
shared memory 308K
=========== =======
TOTAL 380.7M
TOTAL, minus reserved VM space 380.2M
Model: Macmini4,1, BootROM MM41.0042.B03, 2 processors, Intel Core 2 Duo, 2.66 GHz, 8 GB, SMC 1.65f2
Graphics: NVIDIA GeForce 320M, NVIDIA GeForce 320M, PCI, 256 MB
Memory Module: BANK 0/DIMM0, 4 GB, DDR3, 1067 MHz, 0x857F, 0x483634353155363446373036364700000000
Memory Module: BANK 1/DIMM0, 4 GB, DDR3, 1067 MHz, 0x857F, 0x483634353155363446373036364700000000
AirPort: spairport_wireless_card_type_airport_extreme (0x14E4, 0x93), Broadcom BCM43xx 1.0 (5.106.198.4.20)
Bluetooth: Version 4.0.5f11, 2 service, 18 devices, 1 incoming serial ports
Network Service: Ethernet, Ethernet, en0
Serial ATA Device: Hitachi HTS725050A9A362, 500.11 GB
Serial ATA Device: Hitachi HTS725050A9A362, 500.11 GB
USB Device: MacBook Air SuperDrive, apple_vendor_id, 0x1500, 0x24100000 / 2
USB Device: Back-UPS RS 1500G FW:865.L3 .D USB FW:L3, 0x051d (American Power Conversion), 0x0002, 0x06200000 / 4
USB Device: BRCM2070 Hub, 0x0a5c (Broadcom Corp.), 0x4500, 0x06600000 / 3
USB Device: Bluetooth USB Host Controller, apple_vendor_id, 0x8218, 0x06630000 / 5
USB Device: IR Receiver, apple_vendor_id, 0x8242, 0x06500000 / 2
FireWire Device: unknown_device, OWC Mercury Elite-AL Pro, 800mbit_speed
FireWire Device: Rev2, Drobo, 800mbit_speed
I've tried deleting the files in ~Library/Application Support/Handbrake and the related Handbrake files in ~Library/Preferences. I've tried the latest nightly build, I've tried repairing permissions, and nothing works.  I don't know why this started all of a sudden and with just this one program.  Can any one help?
Thanks,
--Dave

For those who ever encounter a similar issue, after writing this post I received a message from Drive Genuius that I had bad blocks on my hard drive.  I zero formatted my drive and restored from my latest Time Machine backup.  So far, so good, everything is magically working again...

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