New Motherboard Replace: Part Numbers? and thermal paste?

I am replacing a new motherboard in my computer
-How do I take off the old thermal paste from the CPU and fan, do I use a paper towel? Or is there something safer?
-And how do I put on the new thermal paste and how much of it should I put on the CPU?
-Also what is the difference between  a motherboard that reads on it in the middle:
MCP61PM-HM REV:2.2
15-V06-012200
and another motherboard that reads:
MCP61PM-HM REV:2.2
15-V06-01221
basically that last number on each motherboard, what does it mean and what's the difference between each motherboard?

Otwa, welcome to the forum.
Here is a very good video to help you with removing the thermal paste:
It is basically an advertisement for Arctic Silver products, but Paul from Newegg always does a great job of making a guide.  I have been an overclocker for years and have always used Arctic Silver products.  The two part kit of remover is new to me and something to try next time I replace the paste on a CPU.
I believe that there should be another number in 15-V06-01221.  It should be 12201.  If this is correct, I may be able to answer your questions.
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