Noise/hum in signal chain

When playing electric guitars and basses I'm having problems with hum:
1--noise in my amps (amps are solid state)
2--with guitars or basses plugged directly into a usb interface, there is hum...more hum when the iBook is plugged in than when it is running on battery power
I've tested the guitars, pickups, and cables sufficiently to rule them out as the source. There isn't hum when recording acoustic instruments and voice with microphones.
This leads me to believe there's an issue with the electric in my room/house. I don't have experience with electrical stuff, but I've heard about special power strips that address issues with grounding. Anyone have solutions/suggestions?

I unplugged the speakers cables and the noise was still there -- so it's interference, nothing from the Mac itself. It's like crackily static, and the loudness increased when the Mac started a new download.
I think it's the Wifi!
My old MPro was hardwired to ethernet but I'm using the wireless chip on the nMP until I can run cable over to it. So that radio must be pumping out enough signal to mess with the speakers, that's possible no? I also have Bluetooth turned on for the mouse.
FYI M-Audio DX-4s.

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