Problems (not responding) when monitor not connected

Hi All,
I have been having problems with certain applications when using my macbook without the LED Cinema display connected.  When the monitor is connected there are no problems at all, but if it is disconnected and I try to open Google Chrome it just bounces in the dock for a while and then becomes not "not responsive" in the activity monitor.  When I force quit Chrome, I get the ignore / report dialog and the Chrome window popups very briefly and disappears when I close that dialog.
Similarly if I attempt to open file in Sublime Text it hangs before opening the file dialog and is marked as "not responsive" also.  Same for MS Office (OS X version of office) when trying to open a file.  Other applications like Safari, Firefox and Xcode open ok and the file open dialogs open ok too.
Sometimes if I leave the laptop for a long time (30mins to many hours) the applications will come back and then work.
I have been trying identify the cause for a long time and recently I discovered that the problems only occur when the monitor is disconnected.  If I restart with the monitor connected the problems do not arise.  I tested it repeatedly by connecting and disconnecting the monitor and the issue always corresponded to the monitor being disconnected.
When started in "safe mode" the problems do not occur even with the monitor unplugged.  I also uninstalled a number of applications I thought could causing issues but none of these had any affect.  I also removed all applications from the startup for my account, again no improvement.  I also enabled the guest account to see if it was a problem with my account but the issues occurred as the guest user.
A number of web searches suggested reinstalling Chrome, checking permissions of the application directories and restarting with option + command + p + p held down until the startup sound plays twice.  Not of these suggestions fixed the problem.
My macbook details are as follows:
Macbook Pro 15"
Processor  2.8 GHz Intel Core i7
Memory  8 GB 1067 MHz DDR3
Graphics  NVIDIA GeForce GT 330M 512 MB
Software  OS X 10.9.4 (13E28)
And the monitor is an Apple LED Cinema Display 27"
Hopefully someone can help me resolve this very frustrating problem, my laptop is of little use when not connected to the monitor because of this.
I have pasted the report from Chrome when I force quit it as it may help identify the problem.
Many Thanks,
Stef
Date/Time:       2014-08-30 17:03:41 +0100
OS Version:      10.9.4 (Build 13E28)
Architecture:    x86_64
Report Version:  18
Command:         Chrome
Path:            /Applications/Google Chrome.app/Contents/MacOS/Google Chrome
Version:         37.0.2062.94 (2062.94)
Parent:          launchd [266]
PID:             372
Event:           hang
Duration:        2.14s (process was unresponsive for 2277 seconds before sampling)
Steps:           22 (100ms sampling interval)
Hardware model:  MacBookPro6,2
Active cpus:     4
Fan speed:       2004 rpm
Free pages:      578656 pages (-19039)
Pageins:         2812 pages
Pageouts:        0 pages
Swapins:         0 pages
Swapouts:        0 pages
Process:         Google Chrome [372]
Path:            /Applications/Google Chrome.app/Contents/MacOS/Google Chrome
Architecture:    i386
Parent:          launchd [266]
UID:             501
Task size:       10002 pages (+8647)
Pageins:         2790 pages
CPU Time:        0.467s
Note:            Unresponsive for 2277 seconds before sampling
  Thread 0x951      priority   44-46   cpu time   0.285s
  22 ??? (Google Chrome + 3925) [0x9df55]
    22 main + 24 (Google Chrome) [0x9df78]
      22 ChromeMain + 53 (Google Chrome Framework) [0xa46545]
        22 ??? (Google Chrome Framework + 7655858) [0x11901b2]
          22 ??? (Google Chrome Framework + 7658510) [0x1190c0e]
            22 ??? (Google Chrome Framework + 7656250) [0x119033a]
              22 ??? (Google Chrome Framework + 47227626) [0x374d2ea]
                22 ??? (Google Chrome Framework + 47254250) [0x3753aea]
                  22 ??? (Google Chrome Framework + 47237868) [0x374faec]
                    22 ??? (Google Chrome Framework + 49648175) [0x399c22f]
                      22 ??? (Google Chrome Framework + 47253233) [0x37536f1]
                        18 ??? (Google Chrome Framework + 47240647) [0x37505c7]
                          18 ??? (Google Chrome Framework + 47993441) [0x3808261]
                            18 ??? (Google Chrome Framework + 47999703) [0x3809ad7]
                              18 ??? (Google Chrome Framework + 47995848) [0x3808bc8]
                                18 ??? (Google Chrome Framework + 47998656) [0x38096c0]
                                  18 ??? (Google Chrome Framework + 22601895) [0x1fd10a7]
                                    18 CGLChoosePixelFormat + 117 (OpenGL) [0x8933019]
                                      18 ??? (OpenGL + 39291) [0x893397b]
                                        18 ??? (OpenGL + 24350) [0x892ff1e]
                                          18 IOServiceOpen + 93 (IOKit) [0x571130]
                                            18 io_service_open_extended + 171 (IOKit) [0x5d7254]
                                              18 mach_msg_trap + 10 (libsystem_kernel.dylib) [0x9923f7a]
                                               *18 hndl_mach_scall + 216 (mach_kernel) [0xffffff80002f3d18]
                                                 *18 ??? (mach_kernel + 825933) [0xffffff80002c9a4d]
                                                   *18 mach_msg_overwrite_trap + 195 (mach_kernel) [0xffffff800021e013]
                                                     *18 ipc_kmsg_send + 117 (mach_kernel) [0xffffff80002139c5]
                                                       *18 ipc_kobject_server + 241 (mach_kernel) [0xffffff8000226bc1]
                                                         *18 ??? (mach_kernel + 746651) [0xffffff80002b649b]
                                                           *18 is_io_service_open_extended + 341 (mach_kernel) [0xffffff80006cd3c5]
                                                             *18 AppleMuxControl::newUserClient(task*, void*, unsigned int, OSDictionary*, IOUserClient**) + 80 (AppleMuxControl) [0xffffff7f823f0c36]
                                                               *18 IOWorkLoop::runAction(int (*)(OSObject*, void*, void*, void*, void*), OSObject*, void*, void*, void*, void*) + 62 (mach_kernel) [0xffffff80006af71e]
                                                                 *18 AppleMuxControl::newUserClientGated(void*) + 144 (AppleMuxControl) [0xffffff7f823f0bb2]
                                                                   *18 AppleGraphicsControlClient::start(IOService*) + 36 (AppleMuxControl) [0xffffff7f823f1388]
                                                                     *18 AppleGraphicsControlClient::startEx(IOService*) + 124 (AppleMuxControl) [0xffffff7f823f141c]
                                                                       *18 AppleMuxControl::addTaskToList(IOService*, unsigned int, char*, bool) + 524 (AppleMuxControl) [0xffffff7f823f0158]
                                                                         *18 IOEventSource::sleepGate(void*, unsigned int) + 69 (mach_kernel) [0xffffff80006afdb5]
                                                                           *18 IOGraphicsWorkLoop::sleepGate(void*, unsigned int) + 106 (IOGraphicsFamily) [0xffffff7f80b2b516]
                                                                             *18 lck_mtx_sleep + 78 (mach_kernel) [0xffffff800022d18e]
                                                                               *18 thread_block_reason + 204 (mach_kernel) [0xffffff8000235d5c]
                                                                                 *18 ??? (mach_kernel + 223579) [0xffffff800023695b]
                                                                                    *18 machine_switch_context + 354 (mach_kernel) [0xffffff80002d8262]
                        4  ??? (Google Chrome Framework + 47244521) [0x37514e9]
                          4  ??? (Google Chrome Framework + 1016568) [0xb3b2f8]
                            3  ??? (Google Chrome Framework + 1021417) [0xb3c5e9]
                              3  ??? (Google Chrome Framework + 55143434) [0x3ed9c0a]
                                3  ??? (Google Chrome Framework + 55137460) [0x3ed84b4]
                                  3  ??? (Google Chrome Framework + 55149136) [0x3edb250]
                                    3  ??? (Google Chrome Framework + 55151368) [0x3edbb08]
                                      3  ??? (Google Chrome Framework + 55154184) [0x3edc608]
                                        3  ??? (Google Chrome Framework + 55155008) [0x3edc940]
                                          2  ??? (Google Chrome Framework + 55159092) [0x3edd934]
                                            2  ??? (Google Chrome Framework + 53659382) [0x3d6f6f6]
                                              2  ??? (Google Chrome Framework + 54108127) [0x3ddcfdf]
                                                2  ??? (Google Chrome Framework + 54067136) [0x3dd2fc0]
                                                  1  ??? (Google Chrome Framework + 54067232) [0x3dd3020]
                                                    1  ??? (Google Chrome Framework + 54773811) [0x3e7f833]
                                                      1  ??? (Google Chrome Framework + 54327297) [0x3e12801]
                                                        1  ??? (Google Chrome Framework + 20880463) [0x1e2cc4f]
                                                          1  -[NSWindow initWithContentRect:styleMask:backing:defer:] + 70 (AppKit) [0x55c270a]
                                                            1  -[NSWindow _initContent:styleMask:backing:defer:contentView:] + 1090 (AppKit) [0x55c2b53]
                                                              1  -[NSWindow _commonInitFrame:styleMask:backing:defer:] + 375 (AppKit) [0x55c3382]
                                                                1  -[NSWindow _setWindowNumber:] + 1341 (AppKit) [0x55c45b5]
                                                                  1  -[NSResponder(NSPersistentUISupport) invalidateRestorableState] + 79 (AppKit) [0x55c4b4a]
                                                                    1  -[NSWindow(NSPersistentUISupport) _invalidateRestorableStateOfContents] + 89 (AppKit) [0x55c4c4b]
                                                                      1  +[NSPersistentUIManager sharedManager] + 18 (AppKit) [0x559b6d8]
                                                                        1  _NSEnablePersistentUI + 544 (AppKit) [0x5597595]
                                                                          1  _LSCopyApplicationInformationItem + 112 (LaunchServices) [0xa2c43ef]
                                                                            1  _LSCopyApplicationInformationItemFromSharedMemory(__LSSharedMemoryPage const*, __LSASN const*, void const*, void const**) + 31 (LaunchServices) [0xa2bbd2d]
                                                                              1  <executing in user space>
                                                  1  ??? (Google Chrome Framework + 54069270) [0x3dd3816]
                                                    1  -[NSWindow setCollectionBehavior:] + 273 (AppKit) [0x55dd76e]
                                                      1  -[NSWindow _updateCollectionBehavior] + 68 (AppKit) [0x55dd7ba]
                                                        1  -[NSWindow _effectiveCollectionBehavior] + 195 (AppKit) [0x55c7069]
                                                          1  objc_msgSend + 81 (libobjc.A.dylib) [0x89684e1]
                                                            1  _class_lookupMethodAndLoadCache3 + 55 (libobjc.A.dylib) [0x8968ca3]
                                                              1  lookUpImpOrForward + 203 (libobjc.A.dylib) [0x896ee3f]
                                                                1  _class_getMethodNoSuper_nolock(objc_class*, objc_selector*) + 36 (libobjc.A.dylib) [0x896efc9]
                                                                  1  fixupSelectorsInMethodList(objc_class*, old_method_list*) + 164 (libobjc.A.dylib) [0x8970f34]
                                                                    1  sel_registerNameNoLock + 23 (libobjc.A.dylib) [0x89674f8]
                                                                      1  __sel_registerName + 91 (libobjc.A.dylib) [0x8965fb3]
                                                                        1  __objc_sel_set_get + 17 (libobjc.A.dylib) [0x8967674]
                                                                          1  __objc_sel_set_findBuckets(__objc_sel_set*, objc_selector*) + 66 (libobjc.A.dylib) [0x8975cca]
                                                                            1  <executing in user space>
                                          1  ??? (Google Chrome Framework + 55159846) [0x3eddc26]
                                            1  ??? (Google Chrome Framework + 54057614) [0x3dd0a8e]
                                              1  -[NSWindow makeKeyAndOrderFront:] + 35 (AppKit) [0x56ed2bb]
                                                1  -[NSWindow _makeKeyRegardlessOfVisibility] + 122 (AppKit) [0x56ed377]
                                                  1  -[NSWindow makeKeyWindow] + 72 (AppKit) [0x56f5146]
                                                    1  -[NSWindow _changeKeyAndMainLimitedOK:] + 907 (AppKit) [0x56f54f8]
                                                      1  -[NSWindow becomeKeyWindow] + 1895 (AppKit) [0x56f61d9]
                                                        1  _NXResetCursorState + 72 (AppKit) [0x56fb86b]
                                                          1  +[NSEvent _discardCursorEventsForWindowNumber:criteria:] + 64 (AppKit) [0x56fb901]
                                                            1  FlushSpecificEventsFromQueue + 58 (HIToolbox) [0x7340925]
                                                              1  _MainQueuePreFlush + 18 (HIToolbox) [0x734099f]
                                                                1  PullEventsFromWindowServer + 63 (HIToolbox) [0x73409ee]
                                                                  1  PullEventsFromWindowServerOnConnection(unsigned int, unsigned char, __CFMachPortBoost*) + 99 (HIToolbox) [0x733b7bd]
                                                                    1  CGEventCreateNextEvent + 39 (CoreGraphics) [0x8df87cb]
                                                                      1  CGSGetNextEventRecordInternal + 84 (CoreGraphics) [0x8df8864]
                                                                        1  CGSSnarfAndDispatchDatagrams + 432 (CoreGraphics) [0x8df8b2e]
                                                                          1  CGSDatagramReadStreamDispatchDatagramsWithData + 160 (CoreGraphics) [0x8df8e19]
                                                                            1  CGSDatagramReadStream::dispatch_datagrams() + 47 (CoreGraphics) [0x8df9007]
                                                                              1  CGSDatagramReadStream::dispatch_next_datagram() + 806 (CoreGraphics) [0x8df933a]
                                                                                1  event_datagram_handler + 71 (CoreGraphics) [0x8df9d15]
                                                                                   1  CGSDecodeEventRecord + 182 (CoreGraphics) [0x8df9dd5]
                                                                                     1  CFRelease + 986 (CoreFoundation) [0x674209a]
                                                                                       1  malloc_printf + 40 (libsystem_malloc.dylib) [0x999dc08]
                                                                                         1  <executing in user space>
                            1  ??? (Google Chrome Framework + 1018273) [0xb3b9a1]
                              1  ??? (Google Chrome Framework + 3858567) [0xdf1087]
                                1  ??? (Google Chrome Framework + 3875857) [0xdf5411]
                                  1  ??? (Google Chrome Framework + 3765501) [0xdda4fd]
                                    1  ??? (Google Chrome Framework + 3768288) [0xddafe0]
                                      1  ??? (Google Chrome Framework + 3271392) [0xd61ae0]
                                        1  ??? (Google Chrome Framework + 55086144) [0x3ecbc40]
                                          1  ??? (Google Chrome Framework + 57230730) [0x40d758a]
                                            1  std::_Rb_tree_rotate_left(std::_Rb_tree_node_base*, std::_Rb_tree_node_base*&) + 68 (libstdc++.6.dylib) [0x6a74780]
                                              1  <executing in user space>
  Thread 0x955      DispatchQueue 158919340  priority 48         cpu time   0.002s
  22 _dispatch_mgr_thread + 52 (libdispatch.dylib) [0x9777532]
    22 kevent64 + 10 (libsystem_kernel.dylib) [0x9929992]
     *22 ??? (mach_kernel + 3959520) [0xffffff80005c6ae0]
  Thread 0x95d      priority 46      
  22 thread_start + 34 (libsystem_pthread.dylib) [0x9a24cf2]
    22 _pthread_start + 130 (libsystem_pthread.dylib) [0x9a1f485]
      22 _pthread_body + 144 (libsystem_pthread.dylib) [0x9a1f5fb]
        22 ??? (Google Chrome Framework + 8377381) [0x1240425]
          22 ??? (Google Chrome Framework + 8394240) [0x1244600]
            22 ??? (Google Chrome Framework + 8394017) [0x1244521]
              22 ??? (Google Chrome Framework + 8194938) [0x1213b7a]
                22 ??? (Google Chrome Framework + 8291953) [0x122b671]
                  22 ??? (Google Chrome Framework + 8195569) [0x1213df1]
                    22 ??? (Google Chrome Framework + 7892284) [0x11c9d3c]
                      22 ??? (Google Chrome Framework + 7894351) [0x11ca54f]
                        22 -[NSRunLoop(NSRunLoop) runMode:beforeDate:] + 277 (Foundation) [0x1152f9]
                          22 CFRunLoopRunInMode + 123 (CoreFoundation) [0x679e84b]
                            22 CFRunLoopRunSpecific + 394 (CoreFoundation) [0x679e9ea]
                              22 __CFRunLoopRun + 1393 (CoreFoundation) [0x679f1d1]
                                22 __CFRunLoopServiceMachPort + 169 (CoreFoundation) [0x679fbf9]
                                  22 mach_msg_trap + 10 (libsystem_kernel.dylib) [0x9923f7a]
                                   *22 ipc_mqueue_receive_continue + 0 (mach_kernel) [0xffffff80002167d0]
  Thread 0x95e      priority 46      
  22 thread_start + 34 (libsystem_pthread.dylib) [0x9a24cf2]
    22 _pthread_start + 130 (libsystem_pthread.dylib) [0x9a1f485]
      22 _pthread_body + 144 (libsystem_pthread.dylib) [0x9a1f5fb]
        22 ??? (Google Chrome Framework + 8377381) [0x1240425]
          22 ??? (Google Chrome Framework + 8394240) [0x1244600]
            22 ??? (Google Chrome Framework + 8394017) [0x1244521]
              22 ??? (Google Chrome Framework + 8194938) [0x1213b7a]
                22 ??? (Google Chrome Framework + 8291953) [0x122b671]
                  22 ??? (Google Chrome Framework + 8195569) [0x1213df1]
                    22 ??? (Google Chrome Framework + 7888421) [0x11c8e25]
                      22 ??? (Google Chrome Framework + 8464667) [0x125591b]
                        22 kevent + 10 (libsystem_kernel.dylib) [0x9929976]
                         *22 ??? (mach_kernel + 3959520) [0xffffff80005c6ae0]
  Thread 0x961      priority 46      
  22 thread_start + 34 (libsystem_pthread.dylib) [0x9a24cf2]
    22 _pthread_start + 130 (libsystem_pthread.dylib) [0x9a1f485]
      22 _pthread_body + 144 (libsystem_pthread.dylib) [0x9a1f5fb]
        22 ??? (Google Chrome Framework + 8377381) [0x1240425]
          18 __read + 10 (libsystem_kernel.dylib) [0x9929dba]
           *18 hndl_unix_scall + 216 (mach_kernel) [0xffffff80002f3c38]
             *18 unix_syscall + 471 (mach_kernel) [0xffffff8000640777]
               *18 read_nocancel + 127 (mach_kernel) [0xffffff80005f1ecf]
                 *18 ??? (mach_kernel + 4137150) [0xffffff80005f20be]
                   *18 ??? (mach_kernel + 4155151) [0xffffff80005f670f]
                     *18 msleep + 114 (mach_kernel) [0xffffff80005e3e42]
                       *18 ??? (mach_kernel + 4078613) [0xffffff80005e3c15]
                         *18 lck_mtx_sleep + 78 (mach_kernel) [0xffffff800022d18e]
                           *18 thread_block_reason + 204 (mach_kernel) [0xffffff8000235d5c]
                             *18 ??? (mach_kernel + 223579) [0xffffff800023695b]
                               *18 machine_switch_context + 354 (mach_kernel) [0xffffff80002d8262]
          4  ??? (Google Chrome Framework + 1030915) [0xb3eb03]
            4  ??? (Google Chrome Framework + 1031266) [0xb3ec62]
              4  sleep$UNIX2003 + 86 (libsystem_c.dylib) [0x987cdeb]
                4  sleep$UNIX2003 + 45 (libsystem_c.dylib) [0x987cdc2]
                  4  __semwait_signal + 10 (libsystem_kernel.dylib) [0x9928b76]
                   *4  semaphore_wait_continue + 0 (mach_kernel) [0xffffff800023b570]
  Thread 0x963      priority 46         cpu time   0.003s
  22 thread_start + 34 (libsystem_pthread.dylib) [0x9a24cf2]
    22 _pthread_start + 130 (libsystem_pthread.dylib) [0x9a1f485]
      22 _pthread_body + 144 (libsystem_pthread.dylib) [0x9a1f5fb]
        22 ??? (Google Chrome Framework + 8377381) [0x1240425]
          22 ??? (Google Chrome Framework + 8391859) [0x1243cb3]
            22 ??? (Google Chrome Framework + 8378909) [0x1240a1d]
              19 ??? (Google Chrome Framework + 8381513) [0x1241449]
                19 ??? (Google Chrome Framework + 8352824) [0x123a438]
                  19 pthread_cond_wait$UNIX2003 + 71 (libsystem_pthread.dylib) [0x9a23bd9]
                    19 __psynch_cvwait + 10 (libsystem_kernel.dylib) [0x99287ca]
                     *19 psynch_cvcontinue + 0 (pthread) [0xffffff7f80cdd940]
              3  ??? (Google Chrome Framework + 8381379) [0x12413c3]
                3  ??? (Google Chrome Framework + 8352949) [0x123a4b5]
                  3  pthread_cond_timedwait_relative_np + 47 (libsystem_pthread.dylib) [0x9a22042]
                    3  __psynch_cvwait + 10 (libsystem_kernel.dylib) [0x99287ca]
                     *3  psynch_cvcontinue + 0 (pthread) [0xffffff7f80cdd940]
  Thread 0x964      priority   45-46   cpu time   0.024s
  22 thread_start + 34 (libsystem_pthread.dylib) [0x9a24cf2]
    22 _pthread_start + 130 (libsystem_pthread.dylib) [0x9a1f485]
      22 _pthread_body + 144 (libsystem_pthread.dylib) [0x9a1f5fb]
        22 ??? (Google Chrome Framework + 8377381) [0x1240425]
          22 ??? (Google Chrome Framework + 8394240) [0x1244600]
            22 ??? (Google Chrome Framework + 47282943) [0x375aaff]
              22 ??? (Google Chrome Framework + 8394017) [0x1244521]
                22 ??? (Google Chrome Framework + 8194938) [0x1213b7a]
                  22 ??? (Google Chrome Framework + 8291953) [0x122b671]
                    22 ??? (Google Chrome Framework + 8195569) [0x1213df1]
                      21 ??? (Google Chrome Framework + 8206887) [0x1216a27]
                        21 ??? (Google Chrome Framework + 8353734) [0x123a7c6]
                          21 ??? (Google Chrome Framework + 8354104) [0x123a938]
                            21 ??? (Google Chrome Framework + 8352824) [0x123a438]
                              21 pthread_cond_wait$UNIX2003 + 71 (libsystem_pthread.dylib) [0x9a23bd9]
                                21 __psynch_cvwait + 10 (libsystem_kernel.dylib) [0x99287ca]
                                 *21 psynch_cvcontinue + 0 (pthread) [0xffffff7f80cdd940]
                      1  ??? (Google Chrome Framework + 8206936) [0x1216a58]
                        1  ??? (Google Chrome Framework + 8198231) [0x1214857]
                          1  ??? (Google Chrome Framework + 8196570) [0x12141da]
                            1  ??? (Google Chrome Framework + 8378113) [0x1240701]
                              1  ??? (Google Chrome Framework + 8377963) [0x124066b]
                                1  ??? (Google Chrome Framework + 8372025) [0x123ef39]
                                  1  ??? (Google Chrome Framework + 8369616) [0x123e5d0]
                                    1  ??? (Google Chrome Framework + 1877257) [0xc0d509]
                                      1  ??? (Google Chrome Framework + 1874219) [0xc0c92b]
                                        1  ??? (Google Chrome Framework + 1887433) [0xc0fcc9]
                                          1  ??? (Google Chrome Framework + 45769521) [0x35e9331]
                                            1  ??? (Google Chrome Framework + 9382397) [0x13359fd]
                                              1  ??? (Google Chrome Framework + 10344202) [0x142070a]
                                                1  ??? (Google Chrome Framework + 10426609) [0x14348f1]
                                                  1  ??? (Google Chrome Framework + 10333199) [0x141dc0f]
                                                    1  ??? (Google Chrome Framework + 10327354) [0x141c53a]
                                                      1  _platform_memmove$VARIANT$sse42 + 44 (libsystem_platform.dylib) [0x9a0c33c]
                                                        1  <executing in user space>
  Thread 0x965      priority   42-46   cpu time   0.058s
  22 thread_start + 34 (libsystem_pthread.dylib) [0x9a24cf2]
    22 _pthread_start + 130 (libsystem_pthread.dylib) [0x9a1f485]
      22 _pthread_body + 144 (libsystem_pthread.dylib) [0x9a1f5fb]
        22 ??? (Google Chrome Framework + 8377381) [0x1240425]
          22 ??? (Google Chrome Framework + 8394240) [0x1244600]
            22 ??? (Google Chrome Framework + 47283007) [0x375ab3f]
              22 ??? (Google Chrome Framework + 8394017) [0x1244521]
                22 ??? (Google Chrome Framework + 8194938) [0x1213b7a]
                  22 ??? (Google Chrome Framework + 8291953) [0x122b671]
                    22 ??? (Google Chrome Framework + 8195569) [0x1213df1]
                      18 ??? (Google Chrome Framework + 7888421) [0x11c8e25]
                        18 ??? (Google Chrome Framework + 8464667) [0x125591b]
                          18 kevent + 10 (libsystem_kernel.dylib) [0x9929976]
                           *18 ??? (mach_kernel + 3959520) [0xffffff80005c6ae0]
                      4  ??? (Google Chrome Framework + 7888392) [0x11c8e08]
                        4  ??? (Google Chrome Framework + 8464667) [0x125591b]
                          4  kevent + 10 (libsystem_kernel.dylib) [0x9929976]
                           *4  ??? (mach_kernel + 3959520) [0xffffff80005c6ae0]
  Thread 0x966      priority 46         cpu time   0.005s
  22 thread_start + 34 (libsystem_pthread.dylib) [0x9a24cf2]
    22 _pthread_start + 130 (libsystem_pthread.dylib) [0x9a1f485]
      22 _pthread_body + 144 (libsystem_pthread.dylib) [0x9a1f5fb]
        22 ??? (Google Chrome Framework + 8377381) [0x1240425]
          22 ??? (Google Chrome Framework + 8394240) [0x1244600]
            22 ??? (Google Chrome Framework + 47283071) [0x375ab7f]
              22 ??? (Google Chrome Framework + 8394017) [0x1244521]
                22 ??? (Google Chrome Framework + 8194938) [0x1213b7a]
                  22 ??? (Google Chrome Framework + 8291953) [0x122b671]
                    22 ??? (Google Chrome Framework + 8195569) [0x1213df1]
                      22 ??? (Google Chrome Framework + 8206887) [0x1216a27]
                        22 ??? (Google Chrome Framework + 8353734) [0x123a7c6]
                          22 ??? (Google Chrome Framework + 8354104) [0x123a938]
                            22 ??? (Google Chrome Framework + 8352824) [0x123a438]
                              22 pthread_cond_wait$UNIX2003 + 71 (libsystem_pthread.dylib) [0x9a23bd9]
                                22 __psynch_cvwait + 10 (libsystem_kernel.dylib) [0x99287ca]
                                 *22 psynch_cvcontinue + 0 (pthread) [0xffffff7f80cdd940]
  Thread 0x967      priority 46         cpu time   0.005s
  22 thread_start + 34 (libsystem_pthread.dylib) [0x9a24cf2]
    22 _pthread_start + 130 (libsystem_pthread.dylib) [0x9a1f485]
      22 _pthread_body + 144 (libsystem_pthread.dylib) [0x9a1f5fb]
        22 ??? (Google Chrome Framework + 8377381) [0x1240425]
          22 ??? (Google Chrome Framework + 8394240) [0x1244600]
            22 ??? (Google Chrome Framework + 47283135) [0x375abbf]
              22 ??? (Google Chrome Framework + 8394017) [0x1244521]
                22 ??? (Google Chrome Framework + 8194938) [0x1213b7a]
                  22 ??? (Google Chrome Framework + 8291953) [0x122b671]
                    22 ??? (Google Chrome Framework + 8195569) [0x1213df1]
                      22 ??? (Google Chrome Framework + 8206887) [0x1216a27]
                        22 ??? (Google Chrome Framework + 8353734) [0x123a7c6]
                          22 ??? (Google Chrome Framework + 8354104) [0x123a938]
                            22 ??? (Google Chrome Framework + 8352824) [0x123a438]
                              22 pthread_cond_wait$UNIX2003 + 71 (libsystem_pthread.dylib) [0x9a23bd9]
                                22 __psynch_cvwait + 10 (libsystem_kernel.dylib) [0x99287ca]
                                 *22 psynch_cvcontinue + 0 (pthread) [0xffffff7f80cdd940]
  Thread 0x968      priority 46      
  22 thread_start + 34 (libsystem_pthread.dylib) [0x9a24cf2]
    22 _pthread_start + 130 (libsystem_pthread.dylib) [0x9a1f485]
      22 _pthread_body + 144 (libsystem_pthread.dylib) [0x9a1f5fb]
        22 ??? (Google Chrome Framework + 8377381) [0x1240425]
          22 ??? (Google Chrome Framework + 8394240) [0x1244600]
            22 ??? (Google Chrome Framework + 47283199) [0x375abff]
              22 ??? (Google Chrome Framework + 8394017) [0x1244521]
                22 ??? (Google Chrome Framework + 8194938) [0x1213b7a]
                  22 ??? (Google Chrome Framework + 8291953) [0x122b671]
                    22 ??? (Google Chrome Framework + 8195569) [0x1213df1]
                      22 ??? (Google Chrome Framework + 7888421) [0x11c8e25]
                        22 ??? (Google Chrome Framework + 8464667) [0x125591b]
                          22 kevent + 10 (libsystem_kernel.dylib) [0x9929976]
                           *22 ??? (mach_kernel + 3959520) [0xffffff80005c6ae0]
  Thread 0x969      priority 46         cpu time   0.048s
  22 thread_start + 34 (libsystem_pthread.dylib) [0x9a24cf2]
    22 _pthread_start + 130 (libsystem_pthread.dylib) [0x9a1f485]
      22 _pthread_body + 144 (libsystem_pthread.dylib) [0x9a1f5fb]
        22 ??? (Google Chrome Framework + 8377381) [0x1240425]
          22 ??? (Google Chrome Framework + 8394240) [0x1244600]
            22 ??? (Google Chrome Framework + 47283263) [0x375ac3f]
              22 ??? (Google Chrome Framework + 8394017) [0x1244521]
                22 ??? (Google Chrome Framework + 8194938) [0x1213b7a]
                  22 ??? (Google Chrome Framework + 8291953) [0x122b671]
                    22 ??? (Google Chrome Framework + 8195569) [0x1213df1]
                      19 ??? (Google Chrome Framework + 7888421) [0x11c8e25]
                        19 ??? (Google Chrome Framework + 8464667) [0x125591b]
                          19 kevent + 10 (libsystem_kernel.dylib) [0x9929976]
                           *19 ??? (mach_kernel + 3959520) [0xffffff80005c6ae0]
                      2  ??? (Google Chrome Framework + 7888392) [0x11c8e08]
                        2  ??? (Google Chrome Framework + 8464667) [0x125591b]
                          2  kevent + 10 (libsystem_kernel.dylib) [0x9929976]
                           *2  ??? (mach_kernel + 3959520) [0xffffff80005c6ae0]
                      1  ??? (Google Chrome Framework + 7888102) [0x11c8ce6]
                        1  ??? (Google Chrome Framework + 8465226) [0x1255b4a]
                          1  ??? (Google Chrome Framework + 7887939) [0x11c8c43]
                            1  ??? (Google Chrome Framework + 13816880) [0x1770430]
                              1  ??? (Google Chrome Framework + 13827425) [0x1772d61]
                                1  ??? (Google Chrome Framework + 13818496) [0x1770a80]
                                  1  ??? (Google Chrome Framework + 13813827) [0x176f843]
                                    1  ??? (Google Chrome Framework + 13813409) [0x176f6a1]
                                      1  ??? (Google Chrome Framework + 13795939) [0x176b263]
                                        1  ??? (Google Chrome Framework + 13784767) [0x17686bf]
                                          1  ??? (Google Chrome Framework + 13781523) [0x1767a13]
                                            1  ??? (Google Chrome Framework + 13765917) [0x1763d1d]
                                              1  ??? (Google Chrome Framework + 13774355) [0x1765e13]
                                                1  ??? (Google Chrome Framework + 14682889) [0x1843b09]
                                                  1  ??? (Google Chrome Framework + 14654182) [0x183cae6]
                                                    1  ??? (Google Chrome Framework + 14617201) [0x1833a71]
                                                      1  ??? (Google Chrome Framework + 14591683) [0x182d6c3]
                                                        1  ??? (Google Chrome Framework + 14625114) [0x183595a]
                                                          1  ??? (Google Chrome Framework + 14633254) [0x1837926]
                                                            1  ??? (Google Chrome Framework + 9048365) [0x12e412d]
                                                              1  ??? (Google Chrome Framework + 9210033) [0x130b8b1]
                                                                1  ??? (Google Chrome Framework + 8678110) [0x1289ade]
                                                                  1  ??? (Google Chrome Framework + 8686093) [0x128ba0d]
                                                                    1  ??? (Google Chrome Framework + 8745114) [0x129a09a]
                                                                      1  ??? (Google Chrome Framework + 8699820) [0x128efac]
                                                                        1  ??? (Google Chrome Framework + 8707601) [0x1290e11]
                                                                          1  ??? (Google Chrome Framework + 8719608) [0x1293cf8]
                                                                            1  ??? (Google Chrome Framework + 8728695) [0x1296077]
                                                                              1  ??? (Google Chrome Framework + 8731581) [0x1296bbd]
                                                                                1  <executing in user space>
  Thread 0x96a      priority 46      
  22 thread_start + 34 (libsystem_pthread.dylib) [0x9a24cf2]
    22 _pthread_start + 130 (libsystem_pthread.dylib) [0x9a1f485]
      22 _pthread_body + 144 (libsystem_pthread.dylib) [0x9a1f5fb]
        22 ??? (Google Chrome Framework + 8377381) [0x1240425]
          22 ??? (Google Chrome Framework + 8394240) [0x1244600]
            22 ??? (Google Chrome Framework + 8394017) [0x1244521]
              22 ??? (Google Chrome Framework + 8194938) [0x1213b7a]
                22 ??? (Google Chrome Framework + 8291953) [0x122b671]
                  22 ??? (Google Chrome Framework + 8195569) [0x1213df1]
                    22 ??? (Google Chrome Framework + 8206887) [0x1216a27]
                      22 ??? (Google Chrome Framework + 8353734) [0x123a7c6]
                        22 ??? (Google Chrome Framework + 8354104) [0x123a938]
                          22 ??? (Google Chrome Framework + 8352824) [0x123a438]
                            22 pthread_cond_wait$UNIX2003 + 71 (libsystem_pthread.dylib) [0x9a23bd9]
                              22 __psynch_cvwait + 10 (libsystem_kernel.dylib) [0x99287ca]
                               *22 psynch_cvcontinue + 0 (pthread) [0xffffff7f80cdd940]
  Thread 0x3750     priority 46         cpu time   0.001s
  4 start_wqthread + 30 (libsystem_pthread.dylib) [0x9a24cce]
    4 __workq_kernreturn + 10 (libsystem_kernel.dylib) [0x9929046]
     *4 wq_unpark_continue + 0 (pthread) [0xffffff7f80cdb6ae]
  Thread 0x3751     priority 46      
  4 start_wqthread + 30 (libsystem_pthread.dylib) [0x9a24cce]
    4 __workq_kernreturn + 10 (libsystem_kernel.dylib) [0x9929046]
     *4 wq_unpark_continue + 0 (pthread) [0xffffff7f80cdb6ae]
  Thread 0x3753     priority 46      
  4 start_wqthread + 30 (libsystem_pthread.dylib) [0x9a24cce]
    4 __workq_kernreturn + 10 (libsystem_kernel.dylib) [0x9929046]
     *4 wq_unpark_continue + 0 (pthread) [0xffffff7f80cdb6ae]
  Thread 0x3754     priority 46      
  4 thread_start + 34 (libsystem_pthread.dylib) [0x9a24cf2]
    4 _pthread_start + 130 (libsystem_pthread.dylib) [0x9a1f485]
      4 _pthread_body + 144 (libsystem_pthread.dylib) [0x9a1f5fb]
        4 ??? (Google Chrome Framework + 8377381) [0x1240425]
          4 ??? (Google Chrome Framework + 8394240) [0x1244600]
            4 ??? (Google Chrome Framework + 8394017) [0x1244521]
              4 ??? (Google Chrome Framework + 8194938) [0x1213b7a]
                4 ??? (Google Chrome Framework + 8291953) [0x122b671]
                  4 ??? (Google Chrome Framework + 8195569) [0x1213df1]
                    4 ??? (Google Chrome Framework + 7892284) [0x11c9d3c]
                      4 ??? (Google Chrome Framework + 7894351) [0x11ca54f]
                        4 -[NSRunLoop(NSRunLoop) runMode:beforeDate:] + 277 (Foundation) [0x1152f9]
                          4 CFRunLoopRunInMode + 123 (CoreFoundation) [0x679e84b]
                            4 CFRunLoopRunSpecific + 394 (CoreFoundation) [0x679e9ea]
                              4 __CFRunLoopRun + 1393 (CoreFoundation) [0x679f1d1]
                                4 __CFRunLoopServiceMachPort + 169 (CoreFoundation) [0x679fbf9]
                                  4 mach_msg_trap + 10 (libsystem_kernel.dylib) [0x9923f7a]
                                   *4 ipc_mqueue_receive_continue + 0 (mach_kernel) [0xffffff80002167d0]
  Thread 0x3755     priority 46      
  4 thread_start + 34 (libsystem_pthread.dylib) [0x9a24cf2]
    4 _pthread_start + 130 (libsystem_pthread.dylib) [0x9a1f485]
      4 _pthread_body + 144 (libsystem_pthread.dylib) [0x9a1f5fb]
        4 ??? (Google Chrome Framework + 8377381) [0x1240425]
          4 ??? (Google Chrome Framework + 8394240) [0x1244600]
            4 ??? (Google Chrome Framework + 8394017) [0x1244521]
              4 ??? (Google Chrome Framework + 8194938) [0x1213b7a]
                4 ??? (Google Chrome Framework + 8291953) [0x122b671]
                  4 ??? (Google Chrome Framework + 8195569) [0x1213df1]
                    3 ??? (Google Chrome Framework + 8206874) [0x1216a1a]
                      3 ??? (Google Chrome Framework + 8354068) [0x123a914]
                        3 ??? (Google Chrome Framework + 8352949) [0x123a4b5]
                          3 pthread_cond_timedwait_relative_np + 47 (libsystem_pthread.dylib) [0x9a22042]
                            3 __psynch_cvwait + 10 (libsystem_kernel.dylib) [0x99287ca]
                             *3 psynch_cvcontinue + 0 (pthread) [0xffffff7f80cdd940]
                    1 ??? (Google Chrome Framework + 8206887) [0x1216a27]
                      1 ??? (Google Chrome Framework + 8353734) [0x123a7c6]
                        1 ??? (Google Chrome Framework + 8354104) [0x123a938]
                          1 ??? (Google Chrome Framework + 8352824) [0x123a438]
                            1 pthread_cond_wait$UNIX2003 + 71 (libsystem_pthread.dylib) [0x9a23bd9]
                              1 __psynch_cvwait + 10 (libsystem_kernel.dylib) [0x99287ca]
                               *1 psynch_cvcontinue + 0 (pthread) [0xffffff7f80cdd940]
  Thread 0x3756     priority 46      
  4 thread_start + 34 (libsystem_pthread.dylib) [0x9a24cf2]
    4 _pthread_start + 130 (libsystem_pthread.dylib) [0x9a1f485]
      4 _pthread_body + 144 (libsystem_pthread.dylib) [0x9a1f5fb]
        4 ??? (Google Chrome Framework + 8377381) [0x1240425]
          4 ??? (Google Chrome Framework + 8394240) [0x1244600]
            4 ??? (Google Chrome Framework + 8394017) [0x1244521]
              4 ??? (Google Chrome Framework + 8194938) [0x1213b7a]
                4 ??? (Google Chrome Framework + 8291953) [0x122b671]
                  4 ??? (Google Chrome Framework + 8195569) [0x1213df1]
                    4 ??? (Google Chrome Framework + 8206887) [0x1216a27]
                      4 ??? (Google Chrome Framework + 8353734) [0x123a7c6]
                        4 ??? (Google Chrome Framework + 8354104) [0x123a938]
                          4 ??? (Google Chrome Framework + 8352824) [0x123a438]
                            4 pthread_cond_wait$UNIX2003 + 71 (libsystem_pthread.dylib) [0x9a23bd9]
                              4 __psynch_cvwait + 10 (libsystem_kernel.dylib) [0x99287ca]
                               *4 psynch_cvcontinue + 0 (pthread) [0xffffff7f80cdd940]
  Thread 0x3757     priority 46         cpu time   0.018s
  4 thread_start + 34 (libsystem_pthread.dylib) [0x9a24cf2]
    4 _pthread_start + 130 (libsystem_pthread.dylib) [0x9a1f485]
      4 _pthread_body + 144 (libsystem_pthread.dylib) [0x9a1f5fb]
        4 ??? (Google Chrome Framework + 8377381) [0x1240425]
          4 ??? (Google Chrome Framework + 8394240) [0x1244600]
            4 ??? (Google Chrome Framework + 8394017) [0x1244521]
              4 ??? (Google Chrome Framework + 8194938) [0x1213b7a]
                4 ??? (Google Chrome Framework + 8291953) [0x122b671]
                  4 ??? (Google Chrome Framework + 8195569) [0x1213df1]
                    4 ??? (Google Chrome Framework + 8206887) [0x1216a27]
                      4 ??? (Google Chrome Framework + 8353734) [0x123a7c6]
                        4 ??? (Google Chrome Framework + 8354104) [0x123a938]
                          4 ??? (Google Chrome Framework + 8352824) [0x123a438]
                            4 pthread_cond_wait$UNIX2003 + 71 (libsystem_pthread.dylib) [0x9a23bd9]
                              4 __psynch_cvwait + 10 (libsystem_kernel.dylib) [0x99287ca]
                               *4 psynch_cvcontinue + 0 (pthread) [0xffffff7f80cdd940]
  Thread 0x3758     priority 46      
  4 thread_start + 34 (libsystem_pthread.dylib) [0x9a24cf2]
    4 _pthread_start + 130 (libsystem_pthread.dylib) [0x9a1f485]
      4 _pthread_body + 144 (libsystem_pthread.dylib) [0x9a1f5fb]
        4 ??? (Google Chrome Framework + 8377381) [0x1240425]
          4 ??? (Google Chrome Framework + 48597632) [0x389ba80]
            4 mach_msg_trap + 10 (libsystem_kernel.dylib) [0x9923f7a]
             *4 ipc_mqueue_receive_continue + 0 (mach_kernel) [0xffffff80002167d0]
  Thread 0x375a     priority 46      
  3 thread_start + 34 (libsystem_pthread.dylib) [0x9a24cf2]
    3 _pthread_start + 130 (libsystem_pthread.dylib) [0x9a1f485]
      3 _pthread_body + 144 (libsystem_pthread.dylib) [0x9a1f5fb]
        3 ??? (Google Chrome Framework + 8377381) [0x1240425]
          3 ??? (Google Chrome Framework + 8394240) [0x1244600]
            3 ??? (Google Chrome Framework + 8394017) [0x1244521]
              3 ??? (Google Chrome Framework + 8194938) [0x1213b7a]
                3 ??? (Google Chrome Framework + 8291953) [0x122b671]
                  3 ??? (Google Chrome Framework + 8195569) [0x1213df1]
                    3 ??? (Google Chrome Framework + 7892284) [0x11c9d3c]
                      3 ??? (Google Chrome Framework + 7894351) [0x11ca54f]
                        3 -[NSRunLoo

Problem solved!! A colleague suggested that I disable the "Automatic graphic switching" in the Energy Saver settings.  Since disabling the problems appear to have gone away.
Thanks

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