Set Microsoft Outlook as the default mail client.

Every time I am trying to sync my calendar, notes and mail account with my iPhone through iTunes I keep getting a notifactions saying 'Either there is no default mail client or the current mail client cannot fulfill the messaging request. Please run Microsoft Outlook and set it as the default mail client'.
The problem is that Outlook IS the default client.
Why can iTunes not complete this task for me...
Microsoft Office Professional Plus 2010 Build 14.0.4536.1000 64-bit.
Thanks.

I'm getting this and it's really annonying. The Nokia PC Suite provided a basic but functional PC calendar. Surely there's a simple PC client for the iPhone Calendar somewhere. I use Outlook Express and started using Outlook 2002 to manage my calendar but since a recent iTunes upgrade it's stopped working, giving this "default mail client" error. When I set Outlook to be the default mail client it made no difference.
Apple - you've scored an own goal here. Something that did work now doesn't work, and the only thing that's changed is your software.
I don't doubt it's down to compatability with M$ Outlook Add-ins, but they've not changed.

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