Access and permission issue

I am able to connect to the online SharePoint server, but when I try to open an access database that lives on SharePoint it gives me an error that just says "something went wrong". HELP!! I was able to access this database before I change my
Microsoft account primary alias, and removed the old one. Thanks in advanced!

Is this for office 365 or a local, on-premises SharePoint server?
Have you checked the server logs or the ULS logs?

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