Biztalk RFC calls sometimes not releasing order for a few minutes

If biztalk receives two messages (status updates) for the same order in a row, there are times when the second update fails because with the message "status not allowed". This situation does not occur when a different order is updated in between.
Can somebody tell me how to close the connection or end the transaction so that we can prevent these failures.

Not sure how solid of a solution this is. But it looks like it was a software problem after all.
Restoring back to factory settings using the original OS X disc, and updating to the latest Mountain Lion 10.8.3 stopped all the random shut downs.

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