Can't open files in Photoshop CS3...Please Help!!

So last night I was downloading some pictures off my CF cards and apparently I have way too many pictures on my pc and it's full! So I stopped downloading and started deleting!
But while I was doing that, I tried to open some images in photoshop and it just freezes up. The dialog box pops up for a brief second when I try to open the image and then it just disappears. Then I can't click on anything. I have to "ctrl-alt-del" to even shut photoshop down. Does any one know what's up or how I can fix it?
I'm using CS3 and windows xp if that matters...
I have two drives. The drive that I have photoshop on has 184GB left on it...so plenty of space. The other drive...the one I store photos on...only has 32GB left.
I deleted a bunch of photos (need to go buy more DVD's to back up so I can delete more), uninstalled photoshop, cleaned up both hard drives, re-installed photoshop....and it's still doing the same thing. I don't know what else to do....

Cyndi -
I would start with the easiest thing Archive the preference file to your desktop then we can continue from there if that doesnt work.
- Close PS
- Type this into your run menu
%appdata%/adobe/adobe photoshop cs3/
- Now drag the Adobe Photoshop CS3 Settings folder onto your desktop
- Keep the adobe folder window open
- Launch PS
- If this works then there was something corrupted in the preferences somewhere
- If this doesnt work then delete the newly created preference folder from the adobe folder and drag the one from your desktop back into the adobe folder.
Hope this helps.
-Rilla

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