CD opens on boot, restart, G5 PowerMac

Whenever I reboot my computer or restart it, the cd will open on boot regardless of if it is empty or has a CD/DVD in it, any ideas on how I can fix this ? otherwise the CD works fine.
I want to boot from my OS X disk on boot, but the cd opens, so it is preventing me from doing that.

Holding down the mouse button opens the optical drive on startup. So my guess is that one of your USB devices is simulating the mouse button being held down during the initial power up.
I would trouble-shoot this by disconnecting all of your USB devices except for a standard Apple keyboard and mouse, then try starting up. If that fixes the problem, connect one device at a time (counting a USB hub as one device) to determine if one device makes the problem occur.

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