Communication Channel RFC Sender getting error suddenly

Hello gurus,
I'd like to ask you about a problem, we have many interfaces from RFC to SOAP synchronous, the CC RFC sender, in an average of once per day, gets into red colour with this error:
Sender channel 'CC_RFC_SENDER_L0_MAESTROS' for party '', service 'BS_LD0_100'
Error can not instantiate RfcPool caused by:
com.sap.aii.adapter.rfc.RfcAdapterException: error
initializing RfcServerPool:com.sap.aii.adapter.rfc.core.repository.RfcRepositoryException:
can not connect to destination system due to: com.sap.mw.jco.JCO$Exception: (102) RFC_ERROR_COMMUNICATION:
Connect to SAP gateway failed
Connect_PM TYPE=A ASHOST=10.1.4.191 SYSNR=00 GWHOST=10.1.4.191 GWSERV=sapgw00 PCS=1
LOCATION CPIC (TCP/IP) on local host with Unicode
ERROR partner 'XX.X.X.XXX:sapgw00' not reached
TIME Thu May 27 03:56:04 201
RELEASE 711
COMPONENT NI (network interface)
VERSION 39
RC -10
MODULE nixxi.cpp
LINE 3151
DETAIL NiPConnect2: 10.1.4.191:3300
SYSTEM CALL connect
ERRNO 111
ERRNO TEXT Connection refused
COUNTER 5
I don't know the reason of this.. but simply just stopping and starting the CC it gets into green colour again..
Does anyone know how to solve this?
Regards,
Juan.

Hi,
This happens if the RFC connection pool is not instantiated or may be cache failed to auto-refresh....And manual restart of RFC channel resolves it.
Refer page 8 in the RFC troubleshooting guide.
http://www.sdn.sap.com/irj/scn/go/portal/prtroot/docs/library/uuid/f3f93ee7-0c01-0010-2593-d7c28b5377c2?quicklink=index&overridelayout=true
Thanks
Swarup

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