Creating two layouts for same document

Question

I have a document to produce in CS5 that I am hoping to can have two different layouts. The first is 8.5 x 11 that is to be saved as a PDF for customers to access and print from our website. The second goes to a printer where it is to be produced as a double-folded, two sided, single sheet. The folded document has six pages total that is to be put into a binder. The foldable version has three pages to a side. How do I best accomplish this?
Any suggestions?

Answer 1

Eugene is 100% right when he tells you to design for print, first. However, I would use a slightly different tactic:
1) Design for print on letterhalf-sized pages.
2) Make sure that your entire document is one big story with threaded text frames.
3) Make sure that your entire document is perfectly styled with character and paragraph styles. No overrides anywhere in the whole document.
4) Export an RTF of your text.
5) Place that RTF in your 8.5 x 11 layout.
6) That layout has styles with the same names, but the font sizes etc. might be different. So, when you place it, the same text will automagically acquire the styles for your web-distro PDF.
I'd do that because I would expect that placing the letterhalf pages in full letter-size pages for PDF export could be kind of annoying with wrong or different margins, lack of availabilty to manipulate hyperlinks, and etc. Much depends on what you need from your PDFs to be distributed on the web - links? Different graphics? Graphics in different places? In many (most) cases, Eugene's plan is a lot less work than mine.