ITunes Not Responding/Cannot Sync iPhone since Firmware 3.0

Since I installed 3.0 on my iPhone, iTunes keeps crashing when i connect my iPhone, i can no longer sync it with iTunes. When I connect the iPhone, iTunes stops responding.
I have restarted my PC and my iPhone and have even un-installed and re-installed iTunes from my PC.
It is really frustrating because i recently trialed Mobile Me but decided to cancel the trail as i didnt feel i would use it, after i cancelled my account i lost ALL my contacts and calandar entries and need to sync my iPhone with Outlook to get them back.
I have not downloaded any Podcasts, I have uninstalled anything i downloaded on my Lappy since the last time my iPhone worked with iTunes and nothing I do helps.
It's soooo annoying!
Please help!
Thanks.
Mac.

I am running Vista and have the not responding ever since Itunes went to 8. I do not subscribe to podcasts, TV shows or anything but music and removing the rest from preferences makes no difference.
If I have my iPhone plugged in before I start iTunes then I can very occassionally get it to work but most of the time it fails.
I have noticed that if iTunes starts accessing the Store then it will sync the iPhone but otherwise it stops responding. Restarting the Apple Mobile Device service makes no difference.
iTunes works fine with my Nano 8Gb.

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