Please help! Software doesn't work

Hello all,
I'm sort of having a major issue here. Almost every single program that I installed on my iMac does not open — including Google SketchUp for Mac, Call of Duty 2 for Mac (it's Universal, and yes I put the disc in), RollerCoaster Tycoon 3 (not Universal but it ran before!), Railroad Tycoon 3 (also not Universal, but it also ran before), and all Microsoft Office applications. The icon for each thing just bounces once or twice before it stops. I have nothing else open (besides Finder).
I also notice something odd in Activity Monitor — I have not 1, not 2, not 3, but 4! AppleSpells running. (One is taking more threads than the others.)
I also noticed that the "applicaton" loginwindow was open (it's normally not).
Core/root/whatever processes were: Speech Synthesis Server, loginwindow, mdimport, pbs, ATSServer, SystemUIServer, AppleSpell, UniversalAccessApp (huh? I don't need Universal Access...) AppleSpell, AppleSpell, AppleSpell, aped, and iTunes Helper.
Can somebody please help me?
Thanks,
-Joe

It would appear that you need some repairs, let's start simple. Restart and when you hear the bong hold down the shift key. This will start you up in Safe Mode and it should say that in the startup screen.
Then restart again normally and run Repair Permissions with Disk Utility. See if that helps.
Note that is you've disable fonts in Font Book they will no longer be disabled after the safe boot because it deletes all font caches, which actually might be what solves your problem.
Kevin

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Moderator edit: Title adjusted to better reflect message content

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You found me! Thanks for the logs. They confirmed what I was suspecting: a font problem is causing any application built on Windows Presentation Foundation (WPF) to crash. Based on our research there are two potential issues. The fixes are pretty easy.
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