Problems with User profile Application not available

Hi
Have a 2 tier SP 2010, with SQL server and a single SharePoint2010 server. We have a problem with the User profile Application service.
The main problem is that we cannot go to "Edit" under Manage User Profiles. If we want to edit a user, we just get an error:
"Microsoft.Office.Server.UserProfiles.UserProfileApplicationNotAvailableException: No User Profile Application available to service the request. Contact your farm administrator."
When rebooting the server, we get the following in event viewer: Warning: ASP.NET 2.0.50727.0
Event code: 3005 
Event message: An unhandled exception has occurred. 
Event time: 2/5/2015 12:25:25 PM 
Event time (UTC): 2/5/2015 11:25:25 AM 
Event ID: 84d104331476453b88c60a37d7a0b8fe 
Event sequence: 9 
Event occurrence: 1 
Event detail code: 0 
Application information: 
    Application domain: /LM/W3SVC/1212406818/ROOT-1-130676090755160256 
    Trust level: WSS_Minimal 
    Application Virtual Path: / 
    Application Path: C:\inetpub\wwwroot\wss\VirtualDirectories\14877\ 
    Machine name: SPMACHINE 
Process information: 
    Process ID: 4668 
    Process name: w3wp.exe 
    Account name: domain\spfarm 
Exception information: 
    Exception type: UserProfileApplicationNotAvailableException 
    Exception message: No User Profile Application available to service the request. Contact your farm administrator. 
Request information: 
    Request URL: http://sp2010:2010/_layouts/ProfMngr.aspx?ID=51982fe8-4886-4ebd-ad68-f5934656e54d&IsDlg=1 
    Request path: /_layouts/ProfMngr.aspx 
    User host address: ::1 
    User: domain\spfarm 
    Is authenticated: True 
    Authentication Type: NTLM 
    Thread account name: domain\spfarm
Thread information: 
    Thread ID: 15 
    Thread account name: domain\spfarm 
    Is impersonating: False 
    Stack trace:    at Microsoft.SharePoint.Portal.UserProfiles.AdminUI.ProfileAdminPage.get_CurrentApplication()
   at Microsoft.SharePoint.Portal.UserProfiles.AdminUI.ProfileAdminPage.get_CurrentApplicationProxy()
   at Microsoft.SharePoint.Portal.WebControls.ProfileQueryUsers._FillSubtypeCollection()
   at Microsoft.SharePoint.Portal.WebControls.ProfileQueryUsers..ctor()
   at ASP._layouts_profmngr_aspx.__BuildControlProfileQuery()
   at ASP._layouts_profmngr_aspx.__BuildControl__control6(Control __ctrl)
   at ASP._admin_admin_master.__BuildControlPlaceHolderMain()
   at ASP._admin_admin_master.__BuildControl__control21()
   at ASP._admin_admin_master.__BuildControl__control2()
   at ASP._admin_admin_master.__BuildControlTree(_admin_admin_master __ctrl)
   at System.Web.UI.MasterPage.CreateMaster(TemplateControl owner, HttpContext context, VirtualPath masterPageFile, IDictionary contentTemplateCollection)
   at System.Web.UI.Page.get_Master()
   at System.Web.UI.Page.ApplyMasterPage()
   at System.Web.UI.Page.PerformPreInit()
   at System.Web.UI.Page.ProcessRequestMain(Boolean includeStagesBeforeAsyncPoint, Boolean includeStagesAfterAsyncPoint)

Hi Thomas,
Based on the error message, I recommend to verify the things below:
Please make sure that User Profile Service is started in Central Administration.
Please make sure Forefront Identity Manager Service and Forefront Identity Manager Synchronization Service are started in services.msc.
Change the schedule for the "Timer Service Recycle" job to run during off peak hours, when a small amount of timer jobs are running.
Check ULS log for more detailed error message.  For SharePoint 2010, by default, ULS log is at C:\Program Files\Common Files\Microsoft Shared\Web Server Extensions\14\LOGS.
Thanks,
Victoria
Forum Support
Please remember to mark the replies as answers if they help and unmark them if they provide no help. If you have feedback for TechNet Subscriber Support, contact
[email protected]
Victoria Xia
TechNet Community Support

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