Restricting items to User/Responsibilities

We want to restrict certain items to certain users 0nly, or to be more
liberal( since items cant be restricted to users) we would like to
restrict the access of some items to only
selected responsibilities in Inventory and Purchasing transactions
only.
Is it possible first of all to achieve ? And if it is possible then
how do we achieve it? Any standard funbctionlaity or any workaround?
Something like restrictions like Organization access

I note this is a little late to reply to this thread. But was curious - Is you need to
restrict Item Creation or Items being available for Transaction?
The former can be achieved by restricting the access of the Master Items form to
only the few concerned. Even if you want make Org Item form read-only, you cd do that. However, for Transactions there is no way to restrict as of now. And neither can I think of a workaround.

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