Unable to connect to Exchange 2010 Management console after - Exchange 2010 SP3 Rollup 7

We have been having issue with our Exchange Server 2010's Transport Service failing due to a database corruption. I was hoping that maybe applying the Roll-up 7 for Exchange might fix this issue, however after applying the patch we are unable to start the
MSExchangeMailboxAssistants "Error 1053: The service did not respond to the start or control request in a timely fashion."
Then I notice that we were unable to connect to the Management Console or through PowerShell.
Event 1000, Application Error
Faulting application name: MSExchangeMailboxAssistants.exe, version: 14.3.210.2, time stamp: 0x53e2bf34
Faulting module name: KERNELBASE.dll, version: 6.1.7601.18409, time stamp: 0x5315a05a
Exception code: 0xe0434f4d
Fault offset: 0x000000000000940d
Faulting process id: 0x%9
Faulting application start time: 0x%10
Faulting application path: %11
Faulting module path: %12
Report Id: %13
PowerShell error:
Exception calling "TryLoadExchangeTypes" with "2" argument(s): "Could not load file or assembly 'Microsoft.Exchange.Man
agement, Version=14.0.0.0, Culture=neutral, PublicKeyToken=31bf3856ad364e35' or one of its dependencies. Strong name va
lidation failed. (Exception from HRESULT: 0x8013141A)"
At C:\Program Files\Microsoft\Exchange Server\V14\bin\RemoteExchange.ps1:75 char:92
+ $typeLoadResult = [Microsoft.Exchange.Configuration.Tasks.TaskHelper]::TryLoadExchangeTypes <<<< ($ManagementPath, $t
ypeListToCheck)
+ CategoryInfo : NotSpecified: (:) [], MethodInvocationException
+ FullyQualifiedErrorId : DotNetMethodException

Hi,
Please try the following steps to narrow down the issue:
1. Uninstall and reinstall .NET package in Exchange server.
2. Under location C:\Windows\Microsoft.NET\Framework64\v2.0.50727\CONFIG, took a copy of Machine.Config.default, renam it to Machine.config and copy it under this path again.
3. Do IIS reset by running iisreset from a Command Prompt window.
4. Reboot the server and verify whether the Exchange services are started.
Regards,
Winnie Liang
TechNet Community Support

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