I can't get any newly-installed application to launch..

So everything installed on my Lion iMac works absolutely fine. However, I recently tried to re-install Appfresh (an application updater), so I used Appcleaner to uninstall it, grabbed a new download, dragged it to Applications as normal, double-clicked it.. nothing. The icon sits in my dock, and the indicator pulses, continuously, but the application never appears. It's not in the Force Quit menu, and Activity Monitor has no trace of it either.
I thought, okay, something up with Appfresh. But I've since tried a couple of other apps, and a game (Botanicula), and the exact same thing happens. I've done nothing new in the way I've installed them, opened their .dmg files, and dragged the application into Applications, completely normally, but they all do the "sit in the dock and nothing else" thing. If I left-click them once in the dock, they vanish, and that's all I hear of them.
I've tried Disk Utility to do both verify and repair permissions to both the disk and the partition, but that hasn't solved the problem. I'm running the latest 10.7.3 with all patches to remove Flashback, etc.
Any idea what's causing this and how I might get it to work? Thanks in advance.

Is the source download file a zip?
Only use the built in lion uncompression tool -
3rd party ones like "The unarchiver" etc are not working - can either uninstall whatever you are using or check the prefs to untick for zip files. No idea if this is the same for Rars etc
https://discussions.apple.com/thread/3826648?start=0&tstart=0

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[email protected]
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"... after all, He's not a tame lion..."
Be thinking ahead and mark your dance card for NI Week 2015 now: TS 6139 - Object Oriented First Steps

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hi Froudy!
is this your error message?
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Gorgeous Hello All,
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I can't get any newly-installed application to launch..

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