ITunes non-responsive after upgrade

My assistant has iTunes on her PC and it has all but stopped working completely.
Upon clicking to launch it takes a good 10-15 seconds to do anything. Then, selecting anything again takes a good 10-15 seconds for a response...
Is there any background process I need to make sure is running? Do I need to make sure she is running the latest Quicktime version? I did a reinstall of iTunes (did a repair actually), but no difference...
Any ideas?

Okay,
I did as was described in the article and it sped up iTunes somewhat.
There is still a very long lag (5-10 seconds) between selecting anything in iTunes and it actually doing it.
I checked and she had neither "keep music organized" or "copy music to iTunes folder" checked, so I checked those and hit okay... iTunes is organizing.
If this doesn't help, then I am planning to backup her library etc., uninstall iTunes completely, reinstalling iTunes, and restoring her library.

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