Unable to delete a SharePoint 2010 My Sites content Database and IIS Web Site even after changing timeout

Hi,
I am currently having issues with deleting a content database for mysites which has web application http://<servername>:11100. The database was migrated from sharepoint 2010, but on creating web app it timed out (was corrupt due to this).  Problem
is I cannot delete now as I get "Request Timed Out". Even when I try just deleting the Web App or the Content Database individually. I have already updated the timeout on the Central Admin App Pool to 300. This used to work, but no joy now. Seems
like ever since I added this My Sites Web App I am getting this problem.
The setup is 1 Database Server (64GB), 1 Admin Server (24GB) and 3 WFE Servers (12GB each) - all VMS. System is also running PowerPivot. Central Admin is running on a WFE server. Is this setup OK for just one user? Reason I have 3 WFE is this already existed
and App Servers will be scaled out when we start testing. Running 11 Web Applications.
Help appreciated - any ideas?
Thanks.
John.
OH - I tried to delete with powershell and it tells me it requires SHarePoint Administration Service to be running, but the problem is it is already running on the WFE with Central Admin on.

Hi John,
The timeout may cause this issue. But would you let me know the error message when we delete the database?
However, you can delete the web application(my site host) and click delete database and IIS web site option.
Also, you can try to clean cache and check if issue persists:
Please stop SharePoint Timer Service.
Please navigate to the cache.ini file location:                  
Delete all the .xml file and only leave cache.ini in the file location.                  
Edit the Cache.ini file and set it to 1.                 
 Save the Cache.ini file
  Start SharePoint Timer Service. The cache file will be created autumnally.
Any questions, please let me know.
Best Regards,
Dats Luo

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